Protein Alignment Cdk4 and Cdk5

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 130/294 - (44%)
• Similarity: 173/294 - (58%)
• Gaps: 18/294 - (6%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |.::..||||.||||::.|:..|..|||||:||:..::.|||.|.||||.|||:|   .|.|||:
  Fly     4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL---KHKNIVR 65

  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIH 155
            |.:|   |..|.:|  .|||||.:|||....|.| ...:.....:....:||.|:.|.|||.::|
  Fly    66 LIDV---LHSDKKL--TLVFEHCDQDLKKYFDSL-NGEIDMAVCRSFMLQLLRGLAFCHSHNVLH 124

  Fly   156 RDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSV-VVTLWYRAPEVLL-AQPYNSTVDIWSAA 218
            |||||||||::..|.||:||||||:.:|..:|..|. |||||||.|:||. |:.|.:::|:|||.
  Fly   125 RDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAG 189

  Fly   219 CIIFEMFNR-RALFPGTSEKNQLDRIFELTGRPTEQQWPQTIS----VALEHFPQRHPKRPKDFC 278
            ||:.|:.:. |.||||:...:||.:||.:.|.|.|..||....    |||..||.  ........
  Fly   190 CILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPA--ITSWSQLV 252

  Fly   279 PHLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312
            |.|.....|||.|:|....:.|.||.|.::|.||
  Fly   253 PRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	128/292 (44%)
		S_TKc	26..312	CDD:214567	128/292 (44%)
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	130/294 (44%)
		STKc_CDK5	3..286	CDD:143344	128/292 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442456
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940