Protein Alignment Cdk4 and Cdk10

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_038953809.1
• Gene: Cdk10 / 361434
• RGDID: 1304851
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 133/333 - (39%)
• Similarity: 189/333 - (56%)
• Gaps: 49/333 - (14%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            :::||.||||.||.||||||..|..||||||||:...::|:|:|:||||:||.:|   .|.|||:
  Rat    49 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL---RHPNIVE 110

  Fly    91 LYEVC--QFLERDGQLLILLVFEHVEQDLSDLIDRLPK-----------SGMS------------ 130
            |.||.  ..||.     |.||..:.||||:.|::.:|.           :|.|
  Rat   111 LKEVVVGNHLES-----IFLVMGYCEQDLASLLENMPTPFSEAQFCLSCAGHSHSHTLEVLVTSR 170

  Fly   131 -----------PPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGS 184
                       ||.::.:..::|.|:.:||...|||||||..|||::.:|.:|.||||||:.||.
  Rat   171 QRVDALHPVSGPPQVKCILLQVLRGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGV 235

  Fly   185 EMK-LTSVVVTLWYRAPEVLLAQPYNST-VDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELT 247
            .:| :|..||||||||||:||.....:| :|:|:..||:.|:...:.|.|||||.:|:|.|.:|.
  Rat   236 PVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLL 300

  Fly   248 GRPTEQQWP--QTISVALEHFPQRHP-KRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEH 309
            |.|:|..||  ..:.:|.::..::.| ...|...|.|.:....|||.:..||...|.:|..|||.
  Rat   301 GTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATAGDCLES 365

  Fly   310 DYFQQEPL 317
            .||:::||
  Rat   366 SYFKEKPL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	129/326 (40%)
Cdk10	XP_038953809.1	STKc_CDK10	41..384	CDD:173742	133/333 (40%)