Protein Alignment Cdk4 and Cdk1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 125/295 - (42%)
• Similarity: 172/295 - (58%)
• Gaps: 17/295 - (5%)

  Fly    25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            :::::..||||.||.||:.|:.:||.|||:||:|:..::.|||.:.:|||||||:|   .|.|||
  Fly     3 DFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKEL---KHENIV 64

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLP-KSGMSPPTIQRLSRELLTGVDFLHSHRI 153
            .|.:|.....|     |.|:||.:..||...:|.|| ...|....::....::.:.:.|.|..|:
  Fly    65 CLEDVLMEENR-----IYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRV 124

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLLAQP-YNSTVDIWS 216
            :||||||||||:...|.:|:|||||.:::|..::: |..:||||||||||||..| |:..|||||
  Fly   125 LHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWS 189

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPHL 281
            ..||..||..|:.||.|.||.:||.|:|.:...|||..||...|  |..:....|....:...:.
  Fly   190 IGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTS--LPDYKNTFPCWSTNQLTNQ 252

  Fly   282 CKYAD----DLLNKMLSYDLHLRPSALACLEHDYF 312
            .|..|    ||:.|||.||...|.||...|||.||
  Fly   253 LKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	123/292 (42%)
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	123/293 (42%)