Protein Alignment Cdk4 and CG7236

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 103/325 - (31%)
• Similarity: 156/325 - (48%)
• Gaps: 43/325 - (13%)

  Fly     5 RQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMS 69
            ||.:.|..|:..:        |::|:.:|||:||.||:.||..||.:||:|:...|.::..:...
  Fly    37 RQYRPQGSSKMDR--------YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKI 93

  Fly    70 TLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTI 134
            .||||.|||.|   .|.|:|.|.||.:...|     :.||||..|..:...::|.|: |......
  Fly    94 ALREIRLLKNL---KHPNLVSLLEVFRRKRR-----LHLVFEFCELTVLHELERHPQ-GCPEHLT 149

  Fly   135 QRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRA 199
            :::..:.|.||.:.|....:|||:||:|:|:::||.:|:.|||.|:........|..|.|.||||
  Fly   150 KQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRA 214

  Fly   200 PEVLLAQ-PYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTG--RPTEQQ------- 254
            ||:|:.. .|.:.||:|:..|:..|:....||:||.|:.:||..|.:..|  .|...|
  Fly   215 PELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEY 279

  Fly   255 -------WPQTISVALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312
                   .|.|:....:..|.:..:.|...         |.|.|.|..|...|.|.....:|.||
  Fly   280 FKGITLPVPPTLEPLEDKMPAKSQQNPLTI---------DFLKKCLDKDPTKRWSCEKLTKHSYF 335

  Fly   313  312
              Fly   336  335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	97/302 (32%)
		S_TKc	26..312	CDD:214567	97/302 (32%)
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	97/312 (31%)
		Pkinase	50..335	CDD:278497	97/302 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030