Protein Alignment Cdk4 and Cdk11b

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_665709.2
• Gene: Cdk11b / 252879
• RGDID: 628604
• Length: 784
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 126/301 - (41%)
• Similarity: 182/301 - (60%)
• Gaps: 19/301 - (6%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREI-SLLKQLNASNHANIV 89
            :|.||.|.||.||.||||:|..|..|||||::::...:.|.|:::|||| ::||    :.|.|||
  Rat   427 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK----AQHPNIV 487

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRII 154
            .:.|:......|   .|.:|..:||.||..|::.: |....|..::.|..:||:||..||.:.|:
  Rat   488 TVREIVVGSNMD---KIYIVMNYVEHDLKSLMETM-KQPFLPGEVKTLMIQLLSGVKHLHDNWIL 548

  Fly   155 HRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPEVLL-AQPYNSTVDIWSA 217
            |||||..|||:|..|.||:.|||||:.|||.:| .|.|||||||||||:|| |:.|::.||:||.
  Rat   549 HRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 613

  Fly   218 ACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQW------PQTISVALEHFPQRHPKRPKD 276
            .||..|:..::.||||.||.:|::::|:..|.|:|:.|      |....:....:|..:.:  |.
  Rat   614 GCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNDLPAVKKMTFSEYPYNNLR--KR 676

  Fly   277 FCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
            |...|.....||:||.|:|....|.||...|:|:||::.||
  Rat   677 FGALLSDQGFDLMNKFLTYFPGRRVSAEDGLKHEYFRETPL 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	122/294 (41%)
Cdk11b	NP_665709.2	STKc_CDC2L1	421..712	CDD:173741	122/294 (41%)