Protein Alignment Cdk4 and Cdk17

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_006513689.1
• Gene: Cdk17 / 237459
• MGIID: 97517
• Length: 539
• Species: Mus musculus
• Alignment Length: 317
• Identity: 120/317 - (37%)
• Similarity: 184/317 - (58%)
• Gaps: 27/317 - (8%)

  Fly     8 KRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLR 72
            :|.:.:...:.|.|....|.:|..:|||.|.|||:.|..:|.|:||||::|:. :|.|.|.:.:|
Mouse   190 RRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLE-HEEGAPCTAIR 253

  Fly    73 EISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRL 137
            |:||||.|   .|||||.|:::   :..|..|  .||||::::||...:|..... ||...::..
Mouse   254 EVSLLKDL---KHANIVTLHDI---VHTDKSL--TLVFEYLDKDLKQYMDDCGNI-MSMHNVKLF 309

  Fly   138 SRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLA-------KTYGSEMKLTSVVVTL 195
            ..::|.|:.:.|..:::||||||||||::.:|.||:||||||       |||.:|      ||||
Mouse   310 LYQILRGLAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNE------VVTL 368

  Fly   196 WYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTI 259
            |||.|:||| :..|::.:|:|...||.|||.:.|.||||::.:::|..||.|.|.|:::.||...
Mouse   369 WYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVS 433

  Fly   260 S---VALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            |   ....:||:..|:...:..|.|.....:|:.|.|.|:...|..|...::|.||:
Mouse   434 SNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVPAEEAMKHVYFR 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	115/296 (39%)
		S_TKc	26..312	CDD:214567	115/296 (39%)
Cdk17	XP_006513689.1	STKc_PCTAIRE2	201..509	CDD:143377	119/306 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810