Protein Alignment Cdk4 and Cdk10

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_919428.1
• Gene: Cdk10 / 234854
• MGIID: 2448549
• Length: 360
• Species: Mus musculus
• Alignment Length: 299
• Identity: 129/299 - (43%)
• Similarity: 187/299 - (62%)
• Gaps: 16/299 - (5%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            :::||.||||.||.||||||..|..||||||||:...::|:|:|:||||:||.:|   .|.|||:
Mouse    39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL---RHPNIVE 100

  Fly    91 LYEVC--QFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRI 153
            |.||.  ..||.     |.||..:.||||:.|::.:| :..|...::.:..::|.|:.:||.:.|
Mouse   101 LKEVVVGNHLES-----IFLVMGYCEQDLASLLENMP-TPFSEAQVKCIMLQVLRGLQYLHRNFI 159

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPEVLLAQPYNST-VDIWS 216
            ||||||..|||::.:|.:|.||||||:.||..:| :|..||||||||||:||.....:| :|:|:
Mouse   160 IHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWA 224

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWP--QTISVALEHFPQRHP-KRPKDFC 278
            ..||:.|:...:.|.|||||.:|:|.|.:|.|.|:|..||  ..:.:|.::..::.| ...|...
Mouse   225 VGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKF 289

  Fly   279 PHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
            |.|.:....|||.:..||...|.::..|||..||:::||
Mouse   290 PWLSEAGLRLLNFLFMYDPKKRATSGDCLESSYFKEKPL 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	125/292 (43%)
Cdk10	NP_919428.1	STKc_CDK10	31..339	CDD:173742	129/299 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..360