Protein Alignment Cdk4 and dyf-5

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001129786.2
• Gene: dyf-5 / 187442
• WormBaseID: WBGene00001121
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 310
• Identity: 110/310 - (35%)
• Similarity: 171/310 - (55%)
• Gaps: 26/310 - (8%)

  Fly    12 MSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISL 76
            ||.|.|..|    .|.....:|:|.:|.|..|:.:.||:.||:|:::.........|| |||:..
 Worm     1 MSSAVKLAD----RYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMS-LREVKS 60

  Fly    77 LKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLI---DR-LPKSGMSPPTIQRL 137
            ||:|   ||.||:||.||.:  |.|   ::..|||.::::|.:|:   || .|:|     .|:.:
 Worm    61 LKKL---NHPNIIKLREVIR--END---ILYFVFEFMQENLYELMKDRDRYFPES-----VIRNI 112

  Fly   138 SRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEV 202
            ..::|.|:.|:|.:...|||:||:|::.:....:||||||||:...|:...|..|.|.||||||:
 Worm   113 IYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEI 177

  Fly   203 LL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALE-- 264
            || :..|||.:|:|:..||:.|::..|.|||||||.:||.:|..:.|.|.:.:||:...:|..
 Worm   178 LLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMN 242

  Fly   265 -HFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
             .|.|......:.....:.|....|:..|:.::...||:|...|.:.|||
 Worm   243 FRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQ 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	102/293 (35%)
dyf-5	NP_001129786.2	STKc_MAK_like	11..291	CDD:270824	102/293 (35%)