Protein Alignment Cdk4 and Cdk18

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_032821.1
• Gene: Cdk18 / 18557
• MGIID: 97518
• Length: 451
• Species: Mus musculus
• Alignment Length: 320
• Identity: 127/320 - (39%)
• Similarity: 186/320 - (58%)
• Gaps: 30/320 - (9%)

  Fly     5 RQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMS 69
            |..:|..:|.   .|.|....|.:|:.:|||.|.||::.|..:|.|:||||::|:. :|.|.|.:
Mouse   103 RMSRRASLSD---IGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCT 163

  Fly    70 TLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTI 134
            .:||:||||.|   .|||||.|:::   :..|..|  .||||:::.||...:|..... |:...:
Mouse   164 AIREVSLLKDL---KHANIVTLHDL---IHTDRSL--TLVFEYLDSDLKQYLDHCGNL-MNMHNV 219

  Fly   135 QRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLA-------KTYGSEMKLTSVV 192
            :....:||.|:.:.|..:|:||||||||||::.:|.||:||||||       |||.:|      |
Mouse   220 KIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNE------V 278

  Fly   193 VTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWP 256
            ||||||.|:||| :..|::.:|:|...||::||...:.||||::.|.:|..||.|.|.|||:.||
Mouse   279 VTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWP 343

  Fly   257 QTISVA---LEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            ...|::   ..:||:..|:......|.|.....:||:.:|.|:...|.||.|.|.|.|||
Mouse   344 GVTSISEFRAYNFPRYLPQPLLSHAPRLDTEGINLLSSLLLYESKSRMSAEAALNHPYFQ 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	119/296 (40%)
		S_TKc	26..312	CDD:214567	119/296 (40%)
Cdk18	NP_032821.1	PKc_like	115..402	CDD:304357	120/302 (40%)
		PLN00009	118..407	CDD:177649	122/302 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900