Protein Alignment Cdk4 and cdk-1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001022747.1
• Gene: cdk-1 / 176374
• WormBaseID: WBGene00000405
• Length: 332
• Species: Caenorhabditis elegans
• Alignment Length: 314
• Identity: 127/314 - (40%)
• Similarity: 177/314 - (56%)
• Gaps: 34/314 - (10%)

  Fly    20 DGDPF----NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQL 80
            :||..    ::.:|..||||.||.||:.::..|..:||:||:|:...:.|||.:.:|||||||:|
 Worm    12 EGDSVYTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKEL 76

  Fly    81 NASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSP-PTIQRLSRELLTG 144
               .|.|:|.|..|.....|     :.|:||.:..||...:|:|.|....| .|::..:.::|..
 Worm    77 ---QHPNVVGLEAVIMQENR-----LFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQA 133

  Fly   145 VDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLL-AQP 207
            :.|.|..|:||||||||||||.:.|.:|:||||||:..|..::: |..||||||||||:|: ||.
 Worm   134 MCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQR 198

  Fly   208 YNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPK 272
            |:..||:||..||..||..::.||.|.||.::|.|||.:.|.|||.:|....|  |..:....||
 Worm   199 YSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVES--LPDYKATFPK 261

  Fly   273 RPKDFC----------PHLCKYADD----LLNKMLSYDLHLRPSALACLEHDYF 312
            ..::|.          .||   .||    ||..:|.||..||.:|...|.|.||
 Worm   262 WRENFLRDKFYDKKTGKHL---LDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	123/302 (41%)
cdk-1	NP_001022747.1	STKc_CDK1_euk	21..312	CDD:270845	123/303 (41%)