Protein Alignment Cdk4 and Cdk4

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_315841.3
• Gene: Cdk4 / 1276486
• VectorBaseID: AGAMI1_007178
• Length: 302
• Species: Anopheles gambiae
• Alignment Length: 296
• Identity: 202/296 - (68%)
• Similarity: 240/296 - (81%)
• Gaps: 3/296 - (1%)

  Fly    25 NYQELNIIGEGAYGTVYRARDV-ITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANI 88
            ||:||.:||.|||||||||||: ..|.||||||||::|.|:||||||||||.:||||:...|.|:
Mosquito     5 NYEELGVIGTGAYGTVYRARDLKNAGTIVALKKVRVALTEDGVPMSTLREIFMLKQLDTFGHPNV 69

  Fly    89 VKLYEVC--QFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSH 151
            |||.:||  |.|||:|||::.|||||::.||.:.|.|||..||.|.||||||||:|||:||||||
Mosquito    70 VKLLDVCQGQRLEREGQLVLFLVFEHLDHDLDEYIKRLPPKGMPPATIQRLSREMLTGIDFLHSH 134

  Fly   152 RIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQPYNSTVDIWS 216
            |||||||||||||:||.||||:|||||||||..|||||:||||||||||||||.:.|||:|||||
Mosquito   135 RIIHRDLKPQNLLISSDGHLKLADFGLAKTYDFEMKLTTVVVTLWYRAPEVLLGEAYNSSVDIWS 199

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPHL 281
            |.|||.|||.|:||||||:|.|||:|||||||||:|.|||:.||:..|:|.....:.|::|||.|
Mosquito   200 AGCIIAEMFQRQALFPGTAEGNQLERIFELTGRPSEAQWPRGISIVRENFRSTQRREPREFCPKL 264

  Fly   282 CKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
            |..|:|||..||::..|.||||..||.|.||:|||:
Mosquito   265 CDNANDLLKSMLAFSRHERPSARQCLNHAYFKQEPM 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	196/288 (68%)
Cdk4	XP_315841.3	STKc_CDK4_6_like	6..295	CDD:270831	198/291 (68%)