Protein Alignment Cdk4 and Eip63E

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_061506627.1
• Gene: Eip63E / 1276401
• VectorBaseID: AGAMI1_000657
• Length: 533
• Species: Anopheles gambiae
• Alignment Length: 335
• Identity: 124/335 - (37%)
• Similarity: 174/335 - (51%)
• Gaps: 53/335 - (15%)

  Fly     8 KRQKMSQAKKFGDGDPFN----YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPM 68
            :|::.|   .||...||.    |.:|..:|||:|.||::....:|..:||||::|:. .|.|.|.
Mosquito   194 RRKRFS---AFGGDSPFGKSDAYIKLEQLGEGSYATVFKGYSNLTNQVVALKEIRLQ-EEEGAPF 254

  Fly    69 STLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPT 133
            :.:||.||||:|   .|:|||.|:::....|     .:..|||.|..|||..::|.| .|:....
Mosquito   255 TAIREASLLKEL---KHSNIVTLHDIVHTRE-----TLTFVFEFVNTDLSQYMERHP-GGLDHRN 310

  Fly   134 IQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK-------TYGSEMKLTSV 191
            ::....:||.|:.:.|..|::|||:||||||:|..|.||:||||||:       ||..|
Mosquito   311 VRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISETGELKLADFGLARAKSVPSHTYSHE------ 369

  Fly   192 VVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEK-NQLDRIFELTGRPTEQQ 254
            |||||||.|:||| :..|::::|||...||..||......|||..:. :|||:||::.|.|||..
Mosquito   370 VVTLWYRPPDVLLGSTEYSTSLDIWGVGCIFVEMITGMPTFPGIRDTYDQLDKIFKILGTPTEDT 434

  Fly   255 WPQTISVALEHFPQ---------RHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRP----SALAC 306
            ||     .:.|.|.         :..|....| |.|  |..:....|.:..|.|.|    ||...
Mosquito   435 WP-----GVTHLPGYKLQMLGFFKSRKLGLSF-PRL--YDINEGETMATAFLQLNPDNRISADEA 491

  Fly   307 LEHDYFQQEP 316
            |.|.||...|
Mosquito   492 LRHRYFASLP 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	115/307 (37%)
Eip63E	XP_061506627.1	None