Protein Alignment Cdk4 and Cdk1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_307878.4
• Gene: Cdk1 / 1269259
• VectorBaseID: AGAMI1_012530
• Length: 298
• Species: Anopheles gambiae
• Alignment Length: 293
• Identity: 121/293 - (41%)
• Similarity: 167/293 - (56%)
• Gaps: 13/293 - (4%)

  Fly    25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            ::|::..||||.||.||:.|:..||.|||:||:|:...:.|:|.:.:|||||||:|   .|.|:|
Mosquito     3 DFQKIEKIGEGTYGVVYKGRNKHTGEIVAMKKIRLETEDEGIPSTAIREISLLKEL---KHRNVV 64

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGM-SPPTIQRLSRELLTGVDFLHSHRI 153
            .|.:|.....|     :.|:||.:..||...:|.||...| ....::....::...:.|.|..|:
Mosquito    65 SLKDVLMEENR-----LYLIFEFLSMDLKKYMDSLPPEKMIDADLVKSYMYQITAAMLFCHRRRV 124

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPEVLLAQ-PYNSTVDIWS 216
            :||||||||||::.:|.:|:|||||.:::|..:: .|..:||||||||||||.. .|:..|||||
Mosquito   125 LHRDLKPQNLLINKEGVIKVADFGLGRSFGIPVRNYTHEIVTLWYRAPEVLLGSLRYSCPVDIWS 189

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVA--LEHFPQRHPKRPKDFCP 279
            ..||..||..|:.||.|.||.:||.|:|.:...||:..||...|:.  ...||............
Mosquito   190 IGCIFAEMATRKPLFQGDSEIDQLFRMFRILRTPTDDIWPGVTSLPDYKSSFPCWTQNNLASQVS 254

  Fly   280 HLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312
            :|.....|||.|.|.||..||.||...|||.||
Mosquito   255 NLDSAGIDLLQKCLIYDPMLRISAKKILEHKYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	119/290 (41%)
Cdk1	XP_307878.4	STKc_CDK1_euk	3..287	CDD:270845	119/291 (41%)