Protein Alignment Cdk4 and LOC100536316

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_021334474.1
• Gene: LOC100536316 / 100536316
• -ID: -
• Length: 482
• Species: Danio rerio
• Alignment Length: 320
• Identity: 127/320 - (39%)
• Similarity: 186/320 - (58%)
• Gaps: 30/320 - (9%)

  Fly     5 RQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMS 69
            |:|:|..:|:   .|.|....|.:|:.:|||.|.|||:.|..:|.|:||||::|:.. |.|.|.:
Zfish   115 RRLRRTSLSE---IGFGKLETYIKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEY-EEGAPCT 175

  Fly    70 TLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTI 134
            .:||:||||.|   .|||||.|:::..     .:..:.||||::::||...:|.. .|.||...:
Zfish   176 AIREVSLLKNL---KHANIVTLHDIIH-----TEKCLTLVFEYLDRDLKQYLDNC-GSIMSIYNV 231

  Fly   135 QRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLA-------KTYGSEMKLTSVV 192
            :....:||.|:.:.||.:::||||||||||::.:|.||:||||||       ||:.:|      |
Zfish   232 KIFLFQLLRGLAYCHSQKVLHRDLKPQNLLINDKGELKLADFGLARAKSVPTKTFSNE------V 290

  Fly   193 VTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWP 256
            ||||||.|:||| :..|::.:|||...||.:||...|.||||::.:::|..||.:.|.|||..||
Zfish   291 VTLWYRPPDVLLGSTEYSTPIDIWGVGCIFYEMITGRPLFPGSTVEDELHLIFRILGSPTEDSWP 355

  Fly   257 QTIS---VALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            :..|   .....|||...:......|.:.....|||.::|.:|...|.||.|.|.|.||:
Zfish   356 EAYSNENFLSYRFPQYDGEPLVTHAPRITNDGHDLLCQLLQFDARRRVSAEAALRHVYFR 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	119/296 (40%)
LOC100536316	XP_021334474.1	Protein Kinases, catalytic domain	127..414	CDD:473864	120/302 (40%)