DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk4 and LOC100536316

DIOPT Version :9

Sequence 1:NP_001286493.1 Gene:Cdk4 / 36854 FlyBaseID:FBgn0016131 Length:317 Species:Drosophila melanogaster
Sequence 2:XP_021334474.1 Gene:LOC100536316 / 100536316 -ID:- Length:482 Species:Danio rerio


Alignment Length:320 Identity:127/320 - (39%)
Similarity:186/320 - (58%) Gaps:30/320 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMS 69
            |:|:|..:|:   .|.|....|.:|:.:|||.|.|||:.|..:|.|:||||::|:.. |.|.|.:
Zfish   115 RRLRRTSLSE---IGFGKLETYIKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEY-EEGAPCT 175

  Fly    70 TLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTI 134
            .:||:||||.|   .|||||.|:::..     .:..:.||||::::||...:|.. .|.||...:
Zfish   176 AIREVSLLKNL---KHANIVTLHDIIH-----TEKCLTLVFEYLDRDLKQYLDNC-GSIMSIYNV 231

  Fly   135 QRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLA-------KTYGSEMKLTSVV 192
            :....:||.|:.:.||.:::||||||||||::.:|.||:||||||       ||:.:|      |
Zfish   232 KIFLFQLLRGLAYCHSQKVLHRDLKPQNLLINDKGELKLADFGLARAKSVPTKTFSNE------V 290

  Fly   193 VTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWP 256
            ||||||.|:||| :..|::.:|||...||.:||...|.||||::.:::|..||.:.|.|||..||
Zfish   291 VTLWYRPPDVLLGSTEYSTPIDIWGVGCIFYEMITGRPLFPGSTVEDELHLIFRILGSPTEDSWP 355

  Fly   257 QTIS---VALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            :..|   .....|||...:......|.:.....|||.::|.:|...|.||.|.|.|.||:
Zfish   356 EAYSNENFLSYRFPQYDGEPLVTHAPRITNDGHDLLCQLLQFDARRRVSAEAALRHVYFR 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk4NP_001286493.1 STKc_CDK4_6_like 26..312 CDD:270831 119/296 (40%)
S_TKc 26..312 CDD:214567 119/296 (40%)
LOC100536316XP_021334474.1 PKc_like 127..414 CDD:328722 120/302 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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