Protein Alignment Cdk4 and cdk6

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_002934637.2
• Gene: cdk6 / 100489734
• XenbaseID: XB-GENE-985427
• Length: 333
• Species: Xenopus tropicalis
• Alignment Length: 288
• Identity: 137/288 - (47%)
• Similarity: 195/288 - (67%)
• Gaps: 1/288 - (0%)

  Fly    26 YQELNIIGEGAYGTVYRARDVIT-GNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            |:.:..|||||||.|::|||:.. |..||||:||:...|.|:|:||:||:::|:.|....|.|:|
 Frog    15 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVV 79

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRII 154
            :|::||.....|.:..:.||||||:|||:..:|::|..|:....|:.:..:||.|:|||||||::
 Frog    80 RLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPDPGVPSEIIKDMMLQLLRGLDFLHSHRVV 144

  Fly   155 HRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQPYNSTVDIWSAAC 219
            ||||||||:||:|.|.:|:||||||:.|..:|.|||||||||||||||||...|.:.||:||..|
 Frog   145 HRDLKPQNILVTSNGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGC 209

  Fly   220 IIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPHLCKY 284
            |..|||.|:.||.|.|:.:||.:||::.|.|.|::||..::|....|..|.|:..::..|.:.:.
 Frog   210 IFAEMFRRKPLFRGNSDVDQLGKIFDVIGLPEEEEWPHDVAVPRNAFHFRQPQPIENVVPGIDEQ 274

  Fly   285 ADDLLNKMLSYDLHLRPSALACLEHDYF 312
            ..|||.|.|::....|.||.:.|.|.||
 Frog   275 GKDLLIKCLTFSPANRISAYSALSHPYF 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	135/286 (47%)
		S_TKc	26..312	CDD:214567	135/286 (47%)
cdk6	XP_002934637.2	STKc_CDK6	13..302	CDD:270846	135/286 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I1636
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H963
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2818
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D419040at33208
OrthoFinder	1	1.000	-	-		FOG0004605
OrthoInspector	1	1.000	-	-		oto104089
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060