Protein Alignment Cdk4 and cdk13

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_002940845.2
• Gene: cdk13 / 100489599
• XenbaseID: XB-GENE-6040279
• Length: 1391
• Species: Xenopus tropicalis
• Alignment Length: 309
• Identity: 113/309 - (36%)
• Similarity: 172/309 - (55%)
• Gaps: 40/309 - (12%)

  Fly    22 DPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHA 86
            |.|:.  :.|||||.||.||:|:|..||.:|||||||:...:.|.|::.:|||.:|:||   ||.
 Frog   596 DKFDI--IGIIGEGTYGQVYKAKDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL---NHQ 655

  Fly    87 NIVKLYEV-------CQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGM---SPPTIQRLSREL 141
            :|:.:.|:       ..|.:..|  ...||||:::.||..|::    ||:   :...|:...|:|
 Frog   656 SIINMKEIVTDKEDALDFKKDKG--AFYLVFEYMDHDLMGLLE----SGLVHFNEHHIKSFMRQL 714

  Fly   142 LTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSE--MKLTSVVVTLWYRAPEVLL 204
            :.|:|:.|....:|||:|..|:|::::|.:|:||||||:.|.||  ...|:.|:|||||.||:||
 Frog   715 MEGLDYCHKRNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLL 779

  Fly   205 AQP-YNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQ 268
            .:. |:..:|:||..||:.|:|.::.:|....|..||:.|..:.|.|....||..|.  |.:|..
 Frog   780 GEERYSPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRMCGSPCPAVWPDVIK--LPYFNT 842

  Fly   269 RHPKRPKD--------FCPHLCKYADDLLNKMLSYDLHLR---PSALAC 306
            ..||:...        |.|:.   |.||.:.||:.|.:.|   ..||.|
 Frog   843 MKPKKQYRRKLREEFVFIPNA---ALDLFDHMLALDPNKRCTAEQALLC 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	111/305 (36%)
cdk13	XP_002940845.2	STKc_CDK12	590..891	CDD:270847	113/309 (37%)