Protein Alignment Cdk4 and cdk14

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_012819652.1
• Gene: cdk14 / 100125075
• XenbaseID: XB-GENE-943250
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 327
• Identity: 132/327 - (40%)
• Similarity: 185/327 - (56%)
• Gaps: 32/327 - (9%)

  Fly     4 VRQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPM 68
            ||:........:.|||..|  :|::|..:|||:|.|||:.:..:.|.:||||.:|:. .|.|.|.
 Frog   115 VRRHSSPSSPTSPKFGKAD--SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPF 176

  Fly    69 STLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPT 133
            :.:||.||||.|   .|||||.|:::....|     .:.||||:|..||...:|:.| .|::|..
 Frog   177 TAIREASLLKGL---KHANIVLLHDIIHTKE-----TLTLVFEYVHTDLCQYMDKHP-GGLNPEN 232

  Fly   134 IQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK-------TYGSEMKLTSV 191
            ::....:||.|:.::|...|:||||||||||:|..|.||:||||||:       ||.:|
 Frog   233 VKLFLFQLLRGLSYIHQGHILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNE------ 291

  Fly   192 VVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSE-KNQLDRIFELTGRPTEQQ 254
            |||||||.|:||| :..|::.:|:|...||..||....|.|||..: ::||:|||.:.|.|.|:.
 Frog   292 VVTLWYRPPDVLLGSTDYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLILGTPNEET 356

  Fly   255 WPQTISV---ALEHFPQRHPKRPKDFCPHL--CKYADDLLNKMLSYDLHLRPSALACLEHDYFQQ 314
            ||...|:   .||.|.|..||..:.....|  ..:|:||.:|:|......|.||.|.|.||||..
 Frog   357 WPGVHSLPHFKLERFTQYGPKNLRQAWNKLSYVNHAEDLASKLLQCFPKNRLSAQAALNHDYFSD 421

  Fly   315 EP 316
            .|
 Frog   422 LP 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	123/299 (41%)
cdk14	XP_012819652.1	STKc_PFTAIRE1	129..431	CDD:143374	129/313 (41%)