Protein Alignment Cdk4 and cdk6

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001137525.2
• Gene: cdk6 / 100034507
• ZFINID: ZDB-GENE-060503-786
• Length: 324
• Species: Danio rerio
• Alignment Length: 290
• Identity: 141/290 - (48%)
• Similarity: 198/290 - (68%)
• Gaps: 3/290 - (1%)

  Fly    26 YQELNIIGEGAYGTVYRARDVIT-GNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            |:.:..|||||||.||:|||:.. |..||||:||:...|.|:|:||:||:::|:||.:..|.|:|
Zfish    10 YEPVAEIGEGAYGKVYKARDLKNGGRFVALKRVRVQTEEEGMPLSTIREVAVLRQLESFEHPNVV 74

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRII 154
            :|::||.....|.:..:.||||||:|||:..:::.|..|:.|.||:.:..:||.|:|||||||::
Zfish    75 RLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLEKAPDPGVPPETIKDMMYQLLQGLDFLHSHRVV 139

  Fly   155 HRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQPYNSTVDIWSAAC 219
            ||||||||:||:|.|.:|:||||||:.|..:|.|||||||||||||||||...|.:.||:||..|
Zfish   140 HRDLKPQNILVTSGGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGC 204

  Fly   220 IIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRP-KDFCPHLCK 283
            |..|||.||.||.|.|:.:||.:||::.|.|:.:.|||.:.:....|..| |.:| ::..|.:.:
Zfish   205 IFAEMFRRRPLFRGNSDVDQLGKIFDVVGVPSPEDWPQEVGLPQSAFSPR-PAQPIENLVPDMDE 268

  Fly   284 YADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            ....||.:.||::...|.||...|.|.|||
Zfish   269 LGKSLLLRFLSFNPSRRISAYDALSHLYFQ 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	138/287 (48%)
cdk6	NP_001137525.2	None