Protein Alignment CG4927 and KLK1

DIOPT Version :10

• Sequence 1: NP_001033953.1
• Gene: CG4927 / 36852
• FlyBaseID: FBgn0034139
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 75/268 - (27%)
• Similarity: 108/268 - (40%)
• Gaps: 47/268 - (17%)

  Fly   105 IVGGAKAAGREFPFMALLGQRGKNSSQIDWDCGAIIIHPKFVLTAAHCLETSETKEQRLDPNYDG 169
            ||||.:......|:.|.|....      .:.||.|::|.::|||||||:..:
Human    25 IVGGWECEQHSQPWQAALYHFS------TFQCGGILVHRQWVLTAAHCISDN------------- 70

  Fly   170 PKYVVRLGELDYNSTTDDAQPQDFRVLNYVVHPAYG----------EDDDTGSRKNDIAVVEL-E 223
              |.:.||.  :|...|:...|...|.....||.:.          .|:|   ..:|:.::.| |
Human    71 --YQLWLGR--HNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADED---YSHDLMLLRLTE 128

  Fly   224 MEATFSEYVAPACLPLDGGNEQLQVAAAGWGATS-ESGHASSHLLKVSLDRYDVAECSQRLEHKI 287
            ...|.::.|....||.:.........|:|||:.. |:......|..|.|......||.:....|:
Human   129 PADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKV 193

  Fly   288 DVRTQLCAGSRSTSADTCYGDSGGPVFVQHPIYSCLKQVIGITSYGLV-CGVQGLPSVYTKVHLY 351
             ....||.|......|||.||||||:.       |...:.|:||:|.| ||....|||..:|..|
Human   194 -TDFMLCVGHLEGGKDTCVGDSGGPLM-------CDGVLQGVTSWGYVPCGTPNKPSVAVRVLSY 250

  Fly   352 TDWIENIV 359
            ..|||:.:
Human   251 VKWIEDTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	75/265 (28%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	75/265 (28%)