DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4927 and CG3700

DIOPT Version :9

Sequence 1:	NP_001033953.1	Gene:	CG4927 / 36852	FlyBaseID:	FBgn0034139	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	229/360 - (63%)
Similarity:	283/360 - (78%)	Gaps:	14/360 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILLILAVICSILSEFCDNGTGECKELSATDCPSIFFNLHLIRNFVKYCDKSNHIVCCLLP---NN 68
            |||::|.: |:::|:|||||||||||:.:|||.||:|.|||...|||||:.|.||||.:|   .|
  Fly     9 ILLLIASV-SVVTEYCDNGTGECKELTPSDCPVIFYNQHLIGAEVKYCDEFNDIVCCPIPLDHQN 72

  Fly    69 MQPQSQQFSANIGLRRFEKECRRFNEIRTSCRTTPFIVGGAKAAGREFPFMALLG--QRGKNSSQ 131
            ::|..|       .|.|||:|:::||:|::|::|||||||.||:|:|||||||:|  :..|:.|.
  Fly    73 LKPAEQ-------TRPFEKQCKQYNEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSD 130

  Fly   132 IDWDCGAIIIHPKFVLTAAHCLETSETKEQRLDPNYDGPKYVVRLGELDYNSTTDDAQPQDFRVL 196
            |:||||..::||||||||||||||.|:|.:|||||:|.||:||||||||||||||||..|||||:
  Fly   131 INWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVV 195

  Fly   197 NYVVHPAYGEDDDTGSRKNDIAVVELEMEATFSEYVAPACLPLDGGNEQLQVAAAGWGATSESGH 261
            ||||||.|..:|:....|||||:|||:.:|.|:::||..|||.|.||:..||.|||||.|:: |.
  Fly   196 NYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSGNDVQQVTAAGWGFTAD-GV 259

  Fly   262 ASSHLLKVSLDRYDVAECSQRLEHKIDVRTQLCAGSRSTSADTCYGDSGGPVFVQHPIYSCLKQV 326
            .|||||||:|.|:....|.:||...||.|||.||||.|:.||||.||||||:|||||:|.|||||
  Fly   260 KSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQV 324

  Fly   327 IGITSYGLVCGVQGLPSVYTKVHLYTDWIENIVWG 361
            |||.|||||||.||||||||||||||||||:||||
  Fly   325 IGIVSYGLVCGSQGLPSVYTKVHLYTDWIESIVWG 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	173/254 (68%)
CG4927	NP_001033953.1	Tryp_SPc	105..355	CDD:214473	170/251 (68%)
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	173/254 (68%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	170/251 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469098
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25778
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	1	1.000	-	-		FOG0012717
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.010