DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4927 and Plat

DIOPT Version :9

Sequence 1:	NP_001033953.1	Gene:	CG4927 / 36852	FlyBaseID:	FBgn0034139	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_032898.2	Gene:	Plat / 18791	MGIID:	97610	Length:	559	Species:	Mus musculus

Alignment Length:	363	Identity:	107/363 - (29%)
Similarity:	151/363 - (41%)	Gaps:	97/363 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FCDNGTGECKELSATDCPSIFFNLHLIRN---FVKYCDKSNHIVCCLLPNNMQPQSQQFSANIGL 82
            :|.|..|:.:..    |       |::::   ..:|||.|....|                  ||
Mouse   264 YCRNPDGDARPW----C-------HVMKDRKLTWEYCDMSPCSTC------------------GL 299

  Fly    83 RRFEKECRRFNEIRTSCRTTPFIVGGAKAAGREFPFMALLGQRGKNSSQIDWDCGAIIIHPKFVL 147
            |::::...|             |.||........|:.|.:..:.|.|....:.||.::|...:||
Mouse   300 RQYKRPQFR-------------IKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVL 351

  Fly   148 TAAHCLETSETKEQRLDPNY----DGPKYVVRLGELDYNSTTDDAQPQDFRVLNYVVHPAYGEDD 208
            :||||.      .:|..||:    .|..|.|..||          :.|.|.:..|:||..:  ||
Mouse   352 SAAHCF------LERFPPNHLKVVLGRTYRVVPGE----------EEQTFEIEKYIVHEEF--DD 398

  Fly   209 DTGSRKNDIAVVELEME----ATFSEYVAPACLPLDGGNEQL----QVAAAGWGATSESGHASSH 265
            ||  ..||||:::|..:    |..|..|..||||  ..|.||    :...:|:|....|....|.
Mouse   399 DT--YDNDIALLQLRSQSKQCAQESSSVGTACLP--DPNLQLPDWTECELSGYGKHEASSPFFSD 459

  Fly   266 LLKVSLDR-YDVAEC-SQRLEHKIDVRTQLCAGSRSTSA-----DTCYGDSGGPVFVQHPIYSCL 323
            .||.:..| |..:.| ||.|.:|......||||...:..     |.|.||||||:.       |:
Mouse   460 RLKEAHVRLYPSSRCTSQHLFNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGPLV-------CM 517

  Fly   324 --KQ--VIGITSYGLVCGVQGLPSVYTKVHLYTDWIEN 357
              ||  :.||.|:||.||.:.:|.|||||..|.|||.:
Mouse   518 INKQMTLTGIISWGLGCGQKDVPGVYTKVTNYLDWIHD 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	93/276 (34%)
CG4927	NP_001033953.1	Tryp_SPc	105..355	CDD:214473	91/272 (33%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	9/41 (22%)
		Tryp_SPc	311..556	CDD:238113	92/274 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050