DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4927 and svh-1

DIOPT Version :9

Sequence 1:	NP_001033953.1	Gene:	CG4927 / 36852	FlyBaseID:	FBgn0034139	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	100/369 - (27%)
Similarity:	153/369 - (41%)	Gaps:	81/369 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ILAVICSILSEFCDNGTGECKELSATDCPSIFFNLHLIRNFVKYCDKSNHI-VCCLLPNNMQPQS 73
            ||:...:|.|.:..|...:|....::.|                   :.|. :.|:..|.|...|
Worm   646 ILSTNATISSGYNVNCDVDCSIRRSSSC-------------------TRHARISCISQNGMSSAS 691

  Fly    74 QQFSANIGLRRFEKECRRFNEIRTSCRTTPFIVGGAKAAGREFPFMALLGQRGKNSSQIDWDCGA 138
            |     .|||..|...|...:.|.:     .:|||.:.....||:.|.|    :|.:.....|||
Worm   692 Q-----CGLRYVEVNARDAAKSRIA-----RVVGGFETVPGAFPWTAAL----RNKATKAHHCGA 742

  Fly   139 IIIHPKFVLTAAHCLETSETKEQRLDPNYDGPKYVVRLGELDYNSTTDDAQPQDFRVLNYVVHPA 203
            .|:....::|||||.|    :::|:.      .|.|.:|:.|.|.|  |...|.|.:.....:|.
Worm   743 SILDKTHLITAAHCFE----EDERVS------SYEVVVGDWDNNQT--DGNEQIFYLQRIHFYPL 795

  Fly   204 YGEDDDTGSRKNDIAVVELEMEA-TFSEYVAPACLP-----LDGGNEQLQVAAAGWGATSESGHA 262
            |   .|..|  :|||::|:.... .|:||..|.|||     ...|.   |...:|||:   .|..
Worm   796 Y---KDIFS--HDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGR---QCVVSGWGS---MGLR 849

  Fly   263 SSHLLKVSL----DRYDVAECSQRLEHKIDVRTQLCAGSRSTSADTCYGDSGGPVFVQHPIYSCL 323
            .:..|:.:|    :|:|....||  .:....|:..|||......|:|.||||||       ::|.
Worm   850 YAERLQAALIPIINRFDCVNSSQ--IYSSMSRSAFCAGYLEGGIDSCQGDSGGP-------FACR 905

  Fly   324 KQ-----VIGITSYGLVCGVQGLPSVYTKVHLYTDWIENIVWGE 362
            ::     :.|:.|:|..|..:..|.:||.|..|..||..|:.|:
Worm   906 REDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISAIINGQ 949

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	79/267 (30%)
CG4927	NP_001033953.1	Tryp_SPc	105..355	CDD:214473	77/264 (29%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996	8/53 (15%)
		Tryp_SPc	713..945	CDD:238113	79/267 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100