Protein Alignment CG4945 and SBK2

DIOPT Version :10

• Sequence 1: NP_788382.1
• Gene: CG4945 / 36850
• FlyBaseID: FBgn0034137
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001357025.1
• Gene: SBK2 / 646643
• HGNCID: 34416
• Length: 348
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 97/284 - (34%)
• Similarity: 149/284 - (52%)
• Gaps: 9/284 - (3%)

  Fly    23 VDE-FDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPKPYVTLRDFYREFHYGLHLGVHRHIVTT 86
            ||| ::.::.:|:|.:|::|||.||...|.:.||.:|||..:||.|..||..||.||.|..|||.
Human    58 VDELYEEVRPLGQGCYGRVLLVTHRQKGTPLALKQLPKPRTSLRGFLYEFCVGLSLGAHSAIVTA 122

  Fly    87 YDVAFETAGFYVFTQEYAPLGDLTSNVTDS-GVGEVYSKRVAKQLASAIDYMHSKDIVHRDIKLD 150
            |.:..|:|..|.|..|....|||.:.:... |:.:....|.|.|||||::|:|::.:|:||:|.:
Human   123 YGIGIESAHSYSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARGLVYRDLKPE 187

  Fly   151 NVLIYRSDFQRIKLCDFGESFPTGSTVERRNEWLPYSPPEVLEIK--PEGSYKADPSHDVWQFGI 213
            |||:.....:|.||.|||.:.|.|:.:......:||:.||:....  ||| ....|:.|.|..|:
Human   188 NVLVCDPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEG-LPIQPALDAWALGV 251

  Fly   214 VIFVCLTGCLPWQK-AASDDPRYVRYLAWQGGLMMMPLRRTPRLFKLLTSNAQRMFKRFFARISN 277
            ::|..|||..||.: .|..||.|..:|.||..  ..| |..|:.:..|.:.|..:.:........
Human   252 LLFCLLTGYFPWDRPLAEADPFYEDFLIWQAS--GQP-RDRPQPWFGLAAAADALLRGLLDPHPR 313

  Fly   278 RPKSLADVTKFLDDRWLAKTAQKE 301
            |..::..:.:.|...|..:..:.|
Human   314 RRSAVIAIREHLGRPWRQREGEAE 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4945	NP_788382.1	STKc_SBK1	32..293	CDD:270889	92/264 (35%)
SBK2	NP_001357025.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Protein Kinases, catalytic domain	68..329	CDD:473864	92/264 (35%)