DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4945 and bsk146

DIOPT Version :9

Sequence 1:	NP_788382.1	Gene:	CG4945 / 36850	FlyBaseID:	FBgn0034137	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_998006.2	Gene:	bsk146 / 405767	ZFINID:	ZDB-GENE-060313-3	Length:	385	Species:	Danio rerio

Alignment Length:	442	Identity:	132/442 - (29%)
Similarity:	212/442 - (47%)	Gaps:	72/442 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKKPRGNIHKIREFE------LEKIQLVDEFDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPK 59
            ||..|..:...:.|.:      |||:::...:::|:.:|:|.:||:.||.|:...::|.||.:.|
Zfish     1 MSSSPVVSHDILEELQLYTAQNLEKLEVNKYYEVIRELGKGTYGKVDLVIHKIRGSKMALKFLKK 65

  Fly    60 PYVTLRDFYREFHYGLHLGVHRHIVTTYDVAFETAGFYVFTQEYAPLGDLTSNVTDS-GVGEVYS 123
            ....|:.|.||:...|:|.....|:..:.:||||..:|||.|||||.|||...:... |:.|..:
Zfish    66 KSTKLKSFLREYSISLYLSPCPFIINMFGIAFETDEYYVFAQEYAPSGDLFDIIPPQVGLPEPVA 130

  Fly   124 KRVAKQLASAIDYMHSKDIVHRDIKLDNVLIYRSDFQRIKLCDFGESFPTGSTVERRNEWLPYSP 188
            ||...|:|.|::|:|||.:||||||.:|:||:..:.:::||.|||.:...||.|:|.:..:||:.
Zfish   131 KRCVHQVAIALEYLHSKKLVHRDIKPENILIFDKECRKVKLSDFGMARRAGSPVKRVSGTIPYTA 195

  Fly   189 PEVLEIKPEGSYKADPSHDVWQFGIVIFVCLTGCLPWQKAASDDPRYVRYLAWQGGLMMMPLRRT 253
            ||:.:......:..|.|.|||.||:::|..|||..||:||...|..|..::.||       .|||
Zfish   196 PELCDTSKHDGFCVDYSTDVWAFGVLLFCMLTGNFPWEKAMPSDTFYEEFVRWQ-------KRRT 253

  Fly   254 ---PRLFKLLTSNAQRMFKRFFARISNRPKSLADVTKFLDDRWLAKTAQKEMAEYETDELCPSMY 315
               |..::..|..:.|||::..|....|..|:.:|...|..||:.........:
Zfish   254 GAVPSQWRRFTDESLRMFRKLLALEQERRCSVKEVFAHLGHRWMLDGTSGNHHQ----------- 307

  Fly   316 SFHSSPDEKNKLLYTLADCGIETNVDRQQKKNRIKDWIESSIITEEDEEENEETNSASPSSSVSR 380
            |..:|..|:::||           |||.:::                        :.||:::.|.
Zfish   308 SVLNSSSEEDELL-----------VDRMKQQ------------------------TLSPTANTSN 337

  Fly   381 EPLPG---HISSLRKPTSPAESAKEINSTLKDATQKHFDPRTGALQQGPSEM 429
            ...||   |.:|:    |...|....||..:.|  :...|.:..|...|.|:
Zfish   338 AIEPGSANHFTSV----STNSSVSSTNSYERSA--RDSPPTSRILVTTPIEI 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4945	NP_788382.1	SPS1	25..358	CDD:223589	109/336 (32%)
CG4945	NP_788382.1	STKc_SBK1	32..293	CDD:270889	98/264 (37%)
bsk146	NP_998006.2	STKc_SBK1	38..296	CDD:270889	98/264 (37%)
bsk146	NP_998006.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..374		13/51 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	186	1.000	Inparanoid score	I3917
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221624at2759
OrthoFinder	1	1.000	-	-		FOG0002130
OrthoInspector	1	1.000	-	-		mtm6333
orthoMCL	1	0.900	-	-		OOG6_106722
Panther	1	1.100	-	-	O	PTHR24359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X768
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.900