DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4945 and Sbk1

DIOPT Version :9

Sequence 1:	NP_788382.1	Gene:	CG4945 / 36850	FlyBaseID:	FBgn0034137	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_671476.1	Gene:	Sbk1 / 113907	RGDID:	628713	Length:	417	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	100/265 - (37%)
Similarity:	149/265 - (56%)	Gaps:	5/265 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPKPYVTLRDFYREFHYGLHLGVHRHIVTTYDVA 90
            :::::.:|:|.:||:.||.::|:.|:|.||.|.|....|::|.||......|.....|:..:||.
  Rat    53 YELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVV 117

  Fly    91 FETAGFYVFTQEYAPLGDLTSNVTDS-GVGEVYSKRVAKQLASAIDYMHSKDIVHRDIKLDNVLI 154
            |||...|||.|||||.|||...:... |:.|...||..:||..|:|:|||:.:||||||.:|||:
  Rat   118 FETEECYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHSRQLVHRDIKPENVLL 182

  Fly   155 YRSDFQRIKLCDFGESFPTGSTVERRNEWLPYSPPEVLEIKPEGSYKADPSHDVWQFGIVIFVCL 219
            :..:.:|:||.|||.:...|..|:|.:..:||:.|||.:......:..|...|||.||::||..|
  Rat   183 FDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADGFAVDTGVDVWAFGVLIFCVL 247

  Fly   220 TGCLPWQKAASDDPRYVRYLAWQGGLMMMPLRRTPRLFKLLTSNAQRMFKRFFARISNRPKSLAD 284
            ||..||:.|:..|..:..::.||.|    .|...|..::..|..|.|||:|..|....|.....:
  Rat   248 TGNFPWEAASGADAFFEEFVRWQRG----RLPGLPSQWRRFTEPALRMFQRLLALEPERRGPAKE 308

  Fly   285 VTKFL 289
            |.:||
  Rat   309 VFRFL 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4945	NP_788382.1	SPS1	25..358	CDD:223589	100/265 (38%)
CG4945	NP_788382.1	STKc_SBK1	32..293	CDD:270889	100/259 (39%)
Sbk1	NP_671476.1	S_TKc	53..316	CDD:214567	100/265 (38%)
		STKc_SBK1	59..317	CDD:270889	100/259 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..405
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348947
Domainoid	1	1.000	165	1.000	Domainoid score	I3818
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4051
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221624at2759
OrthoFinder	1	1.000	-	-		FOG0002130
OrthoInspector	1	1.000	-	-		mtm9059
orthoMCL	1	0.900	-	-		OOG6_106722
Panther	1	1.100	-	-	LDO	PTHR24359
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X768
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900