DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4945 and sbk1l

DIOPT Version :9

Sequence 1:	NP_788382.1	Gene:	CG4945 / 36850	FlyBaseID:	FBgn0034137	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	XP_012826828.2	Gene:	sbk1l / 100489561	XenbaseID:	XB-GENE-22062467	Length:	361	Species:	Xenopus tropicalis

Alignment Length:	449	Identity:	123/449 - (27%)
Similarity:	186/449 - (41%)	Gaps:	95/449 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QLVDEFDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPKPYVTLRDFYREFHYGLHLGVHRHIVT 85
            |:.|.:.:|:.:|:|.|..:||...|.|...:.||.|.|.......|..|.:..:.|..:..|:.
Frog     6 QIGDHYHVIKKLGQGTFSHVLLARERISGHSVALKFVRKDRTRQAAFLHELNISISLSDYPGIIK 70

  Fly    86 TYDVAFETAGFYVFTQEYAPLGDLTSNV-TDSGVGEVYSKRVAKQLASAIDYMHSKDIVHRDIKL 149
            ||....||..:::||||.||.|.|.|.: ::.|:.|...||.|.|:.:|:||:|.:.:||||:|.
Frog    71 TYPTYIETLDYFIFTQELAPAGTLHSIIESEVGIPEEVVKRCAVQITAALDYIHGRGLVHRDLKP 135

  Fly   150 DNVLIYRSDFQRIKLCDFGESFPTGSTVERRNEWLPYSPPEVLEIKPEGSYKADPSHDVWQFGIV 214
            ||||:...:...|||||||.:...|..|...:..:||.|||:..:||.......||.|:|..||:
Frog   136 DNVLLMDKECYHIKLCDFGFTQNVGFLVPSMSHIIPYMPPELCSLKPNHLLVLGPSMDIWSLGIL 200

  Fly   215 IFVCLTGCLPWQKAASDDPRYVRYLAWQGGLMMMPLRRTPRLFKLLTSNAQRMFKRFFARISNRP 279
            :||.|||..||::|...:.:|..::.|:.....:|   ||.|:...|..|..||....:.|....
Frog   201 LFVALTGYFPWEEALGHNQKYQLFVHWKNNRNYVP---TPILWDRFTQEALDMFLMLLSEIPCAR 262

  Fly   280 KSLADVTKFLDDRWLAKTAQKEMAEYETDELCPSMYSFHSSPDEKNKLLYTLADCGIETNVDRQQ 344
            .....|.|||...|:||.        .:|.|.                        :|.::
Frog   263 HPPDTVLKFLHFPWMAKN--------NSDGLV------------------------VEGDL---- 291

  Fly   345 KKNRIKDWIESSIITEEDEEENEETNSASPSSSVSREPLPGHISSLRKPTSPAESAKEINSTLKD 409
                       :||..||..|               .|:..:|...::.....|:..:|.....|
Frog   292 -----------NIIILEDNNE---------------LPVIEYIIQEQEQVIVVENTDDIEFMYVD 330

  Fly   410 ATQKHFDPRTGALQQGPSEMGQVAMAYSKSASPASNYSTTASTLNNADSLMTLGSRQDL 468
            ..|.|.||.           ..|.|..|::.|                  ::|||..|:
Frog   331 NAQMHLDPN-----------NPVIMLLSENTS------------------LSLGSEIDI 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4945	NP_788382.1	SPS1	25..358	CDD:223589	99/333 (30%)
CG4945	NP_788382.1	STKc_SBK1	32..293	CDD:270889	92/261 (35%)
sbk1l	XP_012826828.2	STKc_SBK1	17..276	CDD:270889	92/261 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3813
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221624at2759
OrthoFinder	1	1.000	-	-		FOG0002130
OrthoInspector	1	1.000	-	-		mtm9478
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X768
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.970