Protein Alignment CG4945 and SBK3

DIOPT Version :10

• Sequence 1: NP_788382.1
• Gene: CG4945 / 36850
• FlyBaseID: FBgn0034137
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_011524600.1
• Gene: SBK3 / 100130827
• HGNCID: 44121
• Length: 384
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 87/298 - (29%)
• Similarity: 137/298 - (45%)
• Gaps: 54/298 - (18%)

  Fly    22 LVDEFDIIQIVGEGWFGKILLVE-HRGSQTEMVLKAVPKPYVTLRDFYREFHYGLHLGVHRHIVT 85
            |.|::.:|:.:|.|.:|::||.: |:|... :.||.:.:..|....|.|||..|..:..|..::.
Human    64 LRDQYHLIRKLGSGSYGRVLLAQPHQGGPA-VALKLLRRDLVLRSTFLREFCVGRCVSAHPGLLQ 127

  Fly    86 TYDVAFETAGFYVFTQEYAPLGDLTSNVTDSGVGEVYSKRVAKQLASAIDYMHSKDIVHRDIKLD 150
            |.....:|..::.|.|||||.|||:..:.:.|:.|:..|||..|||.|:|::||:.:||.|:|.|
Human   128 TLAGPLQTPRYFAFAQEYAPCGDLSGMLQERGLPELLVKRVVAQLAGALDFLHSRGLVHADVKPD 192

  Fly   151 NVLIYRSDFQRIKLCDFGESFPTGSTVERRNEWLPYSPPEVLEIKPEGSYKADPSHDVWQFGIVI 215
            |||::.....|:.|.|.|.:.|.||........||.:|||:..:.|..:....|:.|.|..|:::
Human   193 NVLVFDPVCSRVALGDLGLTRPEGSPTPAPPVPLPTAPPELCLLLPPDTLPLRPAVDSWGLGVLL 257

  Fly   216 FVCLTGCLPWQKAASDDPRYVRYLAW-------------------------QGGLMMMPLRRTPR 255
            |...|.|.||..|.:.:|.:..:..|                         ||.|.:.|..|:|
Human   258 FCAATACFPWDVALAPNPEFEAFAGWVTTKPQPPQPPPPWDQFAPPALALLQGLLDLDPETRSP- 321

  Fly   256 LFKLLTSNAQRMFKRFFARISNRPKSLADVTKFLDDRW 293
                                   |.::.|   ||.|.|
Human   322 -----------------------PLAVLD---FLGDDW 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4945	NP_788382.1	STKc_SBK1	32..293	CDD:270889	83/286 (29%)
SBK3	XP_011524600.1	Protein Kinases, catalytic domain	74..333	CDD:473864	83/286 (29%)