Protein Alignment CG4945 and mark2b

DIOPT Version :9

• Sequence 1: NP_788382.1
• Gene: CG4945 / 36850
• FlyBaseID: FBgn0034137
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_009301419.1
• Gene: mark2b / 100005996
• ZFINID: ZDB-GENE-080215-4
• Length: 790
• Species: Danio rerio
• Alignment Length: 611
• Identity: 140/611 - (22%)
• Similarity: 247/611 - (40%)
• Gaps: 161/611 - (26%)

  Fly    18 EKIQLVDEFDIIQIVGEGWFGKILLVEHRGSQTEMVLKAVPKPYV---TLRDFYREFHYGLHLGV 79
            |:...:..:.:::.:|:|.|.|:.|..|..:..|:.:|.:.|..:   :|:..:||... :.|..
Zfish    41 EEYPHIGNYRLLKTIGKGNFAKVKLARHVLTSKEVAVKIIDKTQLNSSSLQKVFREVRI-MKLLN 104

  Fly    80 HRHIVTTYDVAFETAGFYVFTQEYAPLGDLTSNVTDSG-VGEVYSKRVAKQLASAIDYMHSKDIV 143
            |.:||..::| .||........|||..|::...:...| :.|..::...:|:.||:.|.|.|.||
Zfish   105 HPNIVKLFEV-IETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIV 168

  Fly   144 HRDIKLDNVLIYRSDFQRIKLCDFGES--FPTGSTVERRNEWLPYSPPEVLEIKPEGSYKAD-PS 205
            |||:|.:|:|:...  ..||:.|||.|  |..|:.::......||:.||:.:.|     |.| |.
Zfish   169 HRDLKAENLLLDAD--MNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGK-----KYDGPE 226

  Fly   206 HDVWQFGIVIFVCLTGCLPWQKAASDDPRYVRYLAWQGGLMMMPLRRTPRLFKLLTSNAQRMFKR 270
            .|||..|::::..::|.||:      |.:.::.|..:      .||...|:...::::.:.:.|:
Zfish   227 VDVWSLGVILYTLVSGSLPF------DGQNLKELRER------VLRGKYRIPFYMSTDCENLLKK 279

  Fly   271 FFARISNRPKSLADVTKFLDDRWLAKTAQKEMAEYETDELCPSMYSFHSSPDEKNKLLYTLADCG 335
            |.  |.|..|..:...:.:.|||:       ...||.|:|.|.:   ...||.|:.   ...|..
Zfish   280 FL--ILNPTKRGSLEQQIMKDRWM-------NVGYEDDDLKPYI---EPQPDYKDP---RRTDIM 329

  Fly   336 IETNVDRQQKKNRIKDWIESSIITEEDEE----------ENEETNSASPSSSVSREPLPG-HISS 389
            ::....:::        ||.|::.::..|          .|.|.:.....|..||   || .:::
Zfish   330 LQMGFSQEE--------IEDSLVKQKYNEVMATYLLLDYRNSELDEGVNLSLKSR---PGSDLTN 383

  Fly   390 LRKPTSPAESAKEINSTLKDA----TQKHFDPR-TGALQQGPSEMGQ--------------VAMA 435
            ...|:.|.:..:.::||.|.|    .|..:..| .|..:.|..:.|:              ::..
Zfish   384 SNAPSPPHKVQRSVSSTQKPARRSTDQGSYSKRPQGENKHGVEDSGRKGSSSSTKVPPSPVISSE 448

  Fly   436 YSKSASPASN--YST--------------TASTLNNADSLMTLGSRQDLLASNLTMYTSMETELN 484
            ..||::|::|  .||              |....|..|||.|.|||..
Zfish   449 RKKSSTPSTNSILSTGTSRSRNSPISERATLGVQNGKDSLSTPGSRAS----------------- 496

  Fly   485 RLGEADPRLNQRTQSNNPLLTTFDVNTNPAAKNSIGVGTRGSSRSILKSSIATAAYPALGAFNHG 549
                        |.|..|:|::                :..|||:....|::|:|:|
Zfish   497 ------------TASAGPVLSS----------------SSSSSRTRHHKSLSTSAHP-------- 525

  Fly   550 QSHSLQQLNQHL-----QTSTGLTPS 570
               |...|:.|.     |.:.|.:||
Zfish   526 ---SPADLHSHRPSDPPQRAPGASPS 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4945	NP_788382.1	SPS1	25..358	CDD:223589	87/339 (26%)
		STKc_SBK1	32..293	CDD:270889	73/267 (27%)
mark2b	XP_009301419.1	STKc_MARK	48..301	CDD:270974	74/275 (27%)
		S_TKc	49..301	CDD:214567	74/274 (27%)
		UBA_MARK2	319..360	CDD:270589	7/51 (14%)
		AMPKA_C_like	691..789	CDD:302605

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910