Protein Alignment DAT and si:ch211-132b12.2

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001038688.1
• Gene: si:ch211-132b12.2 / 571877
• ZFINID: ZDB-GENE-050420-178
• Length: 582
• Species: Danio rerio
• Alignment Length: 603
• Identity: 253/603 - (41%)
• Similarity: 365/603 - (60%)
• Gaps: 42/603 - (6%)

  Fly    25 DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQ 89
            :||..|..|.:|:|:|.|..:.|.|||||||||||||||||||||.:.:|..|:|||.:|.|:||
Zfish     9 EERGNWGSKTEFILAVAGIVIGLGNVWRFPYLCYKNGGGAFLVPYLVFVVTCGVPLFLLETAMGQ 73

  Fly    90 HNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNT 154
            :.::|.||||.||.||.:|||||..||..|...||.:|:||:|.:...||::.|||.||:|||||
Zfish    74 YTQEGGITCWHRLCPLAEGIGYAGQLIVLYSCMYYIIILAWALFYLAFSFSSQLPWASCDNIWNT 138

  Fly   155 PNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRY 219
            ..|          |.:..|..:|    :..:|.|.|                   |:.:|::...
Zfish   139 DAC----------VNLAENKLNL----STPMLLNST-------------------SSVTEFWQHR 170

  Fly   220 ILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGL 284
            :|.|  |.||..:|.|.|::.|||:::::||||.:|||:.::||||:|||.|||.:||:||||||
Zfish   171 VLAL--SGGIEKVGKINWEILLCLIVMWIICYFCVWKGVKSTGKVVYFTATFPYVMLLVLLIRGL 233

  Fly   285 TLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTS 349
            ||||:..|:.:||.|..:.:...:||::|..|:|||...|...|....|||||:.|.|:.:|...
Zfish   234 TLPGALQGVVFYLYPEPARLADPQVWMEAGAQIFFSYALGTASLTVLGSYNKYNYNCYRSSLWLC 298

  Fly   350 FINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMML 414
            .:||:||.||||.:|||||:||...|:.||:||..||||.|:.||.|:|.||....||..||:|:
Zfish   299 LLNSSTSVIAGFAVFSVLGFMAQKQGLPIEEVAESGPGLAFIAYPQAVAMMPFPQLWAACFFIMI 363

  Fly   415 LTLGLDSSFGGSEAIITALSDEFPKIKR---NRELFVAGLFSLYFVVG-LASCTQGGFYFFHLLD 475
            :.||||:.|...|..:|::.|.||.:.|   .||:|:. ||.|:...| |...|:||.|.|.|.|
Zfish   364 ILLGLDTQFVAMEVFMTSVIDLFPTVLRKAGRREIFLL-LFCLFCFFGQLVMVTEGGMYVFQLFD 427

  Fly   476 RYA-AGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGL 539
            .|| :|..:|....||::|:.|::|..:....|.||....|..::.:||:::.||..|...|..|
Zfish   428 YYACSGACLLFLCVFESLAMGWVFGAEKMFGIIEDMTNSRPNYWFMLCWKYLTPIVSLASFVCSL 492

  Fly   540 IGYEPLTYAD-YVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQSM 603
            :.|:|||:.. ||||.||..|||.:|.||::::|..|:.::.:..||::||::.|.:|..:....
Zfish   493 VKYKPLTFNRWYVYPDWAYVLGWLLALSSILLVPGWALGRMFAGKGSIKQRWSHLCSPDTNPHFA 557

  Fly   604 AMVLNGVTTEVTVVRLTD 621
            ..:.|....:..|..:.|
Zfish   558 CKIQNKRHEKTPVTEMED 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	248/575 (43%)
si:ch211-132b12.2	NP_001038688.1	SLC6sbd-TauT-like	11..550	CDD:271387	248/574 (43%)