Protein Alignment DAT and slc6a1l

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_021330952.1
• Gene: slc6a1l / 568985
• ZFINID: ZDB-GENE-041210-296
• Length: 578
• Species: Danio rerio
• Alignment Length: 615
• Identity: 256/615 - (41%)
• Similarity: 375/615 - (60%)
• Gaps: 67/615 - (10%)

  Fly    17 DNDNNSISDE--------RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIML 73
            |.|:|||..|        |.:|.||.|||||.:|:|:.|.|||||||||.||||||||:||...|
Zfish     9 DLDHNSIPVEEKENKIPDRGSWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFTTL 73

  Fly    74 VVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFAS 138
            |..|||||.:|.||||:...|.:..| :|:|:.||:|.|.|:::|:::.||.:||||:|.:.|:|
Zfish    74 VFAGIPLFLLETALGQYTSVGGLGVW-KLIPMMKGVGLAAVVLSFWLNIYYIIIIAWALYYLFSS 137

  Fly   139 FTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVG 203
            ....|||.:|:|.|||..|                                 :.|.|.|||:
Zfish   138 LKAELPWQTCDNPWNTDRC---------------------------------FSNYSLLDTT--- 166

  Fly   204 HVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFT 268
               ...||.:|::.|.:.:|  :.|:.:.|.::|.:...|.:.:::.|||:|||:..:||||:|:
Zfish   167 ---NLSSAVTEFWERNMHQL--TNGLEEPGELRWPLVGTLALSWILVYFSIWKGVEWTGKVVYFS 226

  Fly   269 ALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYAS 333
            |.:||.:|.||..||:||||:..|:.:|:||||:.:.|:|||:|||||:|||.|.|.|.|:|..|
Zfish   227 ATYPYFMLFILFFRGVTLPGAIDGVLFYITPNFNKLLKSEVWLDAATQIFFSYGLGLGSLIALGS 291

  Fly   334 YNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIA 398
            ||.::||||:|:::...|||.||..||.||||::|:|::.....||::|..||||.|:.||.|:.
Zfish   292 YNSFNNNVYRDSVIVCCINSCTSMFAGIVIFSIVGFMSYITKRPIEELAASGPGLAFLAYPQAVT 356

  Fly   399 TMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNR-ELFVAGLFSLYFVVGLAS 462
            .:|.|:.||::||.||:.|||||.|...|..||||.||:|.:.|.| ::|:..:..:.|::|.::
Zfish   357 QLPMSSLWAILFFSMLMMLGLDSQFCTVEGFITALMDEYPTVLRKRKKIFILIVCLVSFIIGFSN 421

  Fly   463 CTQGGFYFFHLLDRY-AAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFV 526
            .||||.|.|.|.|.| |:|..:|..||||.|:::|.||..:|.::|.:|||:.|..:|:.||.:.
Zfish   422 ITQGGLYVFKLFDYYSASGMCLLFLVFFETISIAWFYGAEKFYKNIEEMIGYRPCGFWKQCWIYF 486

  Fly   527 APIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFT 591
            .|...|.:..:..|...|||...||||:|...:||.::.||:|:||...|:...||.|::|||:.
Zfish   487 TPTICLGVFTFSAIEMTPLTLGKYVYPAWGQGVGWLMSLSSMVLIPGYIIYMFFSTKGNIRQRWH 551

  Fly   592 ILTTPWRDQQSMAMVLNGVTTEVTVVRLTD 621
            .:|.|               ||:|...:.|
Zfish   552 KMTKP---------------TELTTSDVND 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	245/571 (43%)
slc6a1l	XP_021330952.1	SLC5-6-like_sbd	15..558	CDD:320982	248/599 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820