Protein Alignment DAT and slc6a16b

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001103944.1
• Gene: slc6a16b / 567809
• ZFINID: ZDB-GENE-070424-95
• Length: 676
• Species: Danio rerio
• Alignment Length: 684
• Identity: 215/684 - (31%)
• Similarity: 330/684 - (48%)
• Gaps: 149/684 - (21%)

  Fly     7 ISKSKTPTPHDNDNNSI------------SDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYK 59
            ::.:|.|.|.|...:.:            ...|:.|..||::.|:.:||:|.|.|||||||||::
Zfish     1 MTSAKPPLPADGQQDEVELRLGLEPEVPLETARDGWDSKVEYFLAQVGFSVGLGNVWRFPYLCHQ 65

  Fly    60 NGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYY 124
            ||||||::.|.:::.:.|:|||::|||.||..|:|:|..|..:.|...||||:..::.|:|..||
Zfish    66 NGGGAFILLYVVLMALVGVPLFFLELAAGQSIRQGSIGVWRHISPKLVGIGYSSCVVCFFVALYY 130

  Fly   125 NVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNE 189
            ||||.||:.:...||...|||..|                    |..||
Zfish   131 NVIIGWSIFYLGNSFQYPLPWEKC--------------------PTEGN---------------- 159

  Fly   190 TYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSL 254
                 |::...|.       |:.:.|| .|...|:.::.|.:.|...:.:..|||..::|...::
Zfish   160 -----STVKECAA-------SSPTAYF-WYRKALDITDSIDETGEFNFILTGCLLAAWVIVCLAM 211

  Fly   255 WKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFF 319
            :|||.:||||::|:::|||.|||..||||:||.|:..||::...|........:||..|||||||
Zfish   212 YKGIKSSGKVMYFSSVFPYVVLLCFLIRGVTLDGASEGIKFMFYPRLEIWADVQVWRQAATQVFF 276

  Fly   320 SLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHT----------- 373
            :||.|||.::||:|||..:||.::||...|.:|..||.:|..|:|:|||:.|.|
Zfish   277 ALGLGFGSVIAYSSYNPRNNNCHRDAFTVSGVNFMTSVLATLVVFAVLGFRAKTIAAECVKRNLK 341

  Fly   374 -------------LGVRIEDV------------ATEG-------------------------PGL 388
                         |.:...||            :|:|                         .||
Zfish   342 ALLKVTSSAPLPVLSINASDVESISLDEYANWYSTQGMELSISDYNITACSLEDELRQGVEETGL 406

  Fly   389 VFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFS 453
            .|:.:..|:...|.|.||:.:||:|||.|||.:.||....|:|.|:|.|..::.::.:|.....:
Zfish   407 AFIAFTEAMTLFPGSPFWSALFFLMLLNLGLSTMFGTMAGILTPLTDTFKTLRNHKLIFTICSCT 471

  Fly   454 LYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRY 518
            :.||:||....:.|.||..:.|.|:|...:::.|.|:.|:|||:||.:||.||::.|:..|....
Zfish   472 VGFVIGLVFTQRCGNYFVTMFDDYSATLPLIIVVIFQTISVSWVYGADRFLEDLKQMLNRPVPVI 536

  Fly   519 WQVCWRFVAPIFLLFITVYGLIG-----------------YEPLTYADYVYPSWANALGWCIAGS 566
            ::..|:||.||.:|     ||:|                 .|..:..|..||.||.|:...:...
Zfish   537 YKYLWKFVCPIAML-----GLLGASLLKMILKRPEYSAWNREKASKEDLPYPDWALAVLIILIII 596

  Fly   567 SVVMIPAVAIFKLL-----STPGSLRQRFTILTT 595
            :.:.:|...|..||     .:|.....|:|...|
Zfish   597 ASLPVPIGYIHSLLLERLGQSPADTEARYTPCAT 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	211/652 (32%)
slc6a16b	NP_001103944.1	SLC6sbd-B0AT-like	33..607	CDD:271364	204/627 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910