Protein Alignment DAT and slc6a15

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001232001.1
• Gene: slc6a15 / 565315
• ZFINID: ZDB-GENE-050420-93
• Length: 741
• Species: Danio rerio
• Alignment Length: 682
• Identity: 233/682 - (34%)
• Similarity: 347/682 - (50%)
• Gaps: 135/682 - (19%)

  Fly    17 DNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLF 81
            :.:.....:||..|..|:.::|:.:||:|.|.|||||||||.||||||:||||.|:|::.|||||
Zfish    58 EEEEEEEEEERPAWGSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPLF 122

  Fly    82 YMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWT 146
            ::|||:||..|:|:|..|..:.|...|||:|..|:.|:|..||||||.|||.:|..||...|||.
Zfish   123 FLELAVGQRIRRGSIGVWNYISPHLGGIGFASCLVCFFVALYYNVIIGWSLFYFSQSFQQPLPWH 187

  Fly   147 SCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSA 211
            .|                    |::.|.::.|.                        ..|..:|:
Zfish   188 EC--------------------PLVKNKTNTYI------------------------EPECEKSS 208

  Fly   212 ASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVL 276
            |:.|: .|.:.|:.|:.|.:.|.:.|.|.||||..:.:...::.|||.:||||::|::||||.||
Zfish   209 ATTYY-WYRVALDISDSISEGGGLNWRMTLCLLAAWTMVCLAMIKGIQSSGKVMYFSSLFPYVVL 272

  Fly   277 LILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNV 341
            :..|.|...|.||..||.:..||....:.:.:||.:|||||||:||.|||.::|::||||..||.
Zfish   273 ICFLARAFLLKGSVDGIIHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNC 337

  Fly   342 YKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDV------------------------- 381
            :.||:|.||||..||.:|..|:|:|||:.|:.:..:..::
Zfish   338 HFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNAKCVEMNTKKIIGFLGKEINPGLIPHHINFS 402

  Fly   382 --------------------------------------ATEGPGLVFVVYPAAIATMPASTFWAL 408
                                                  |.:|.||.|:.:..|:...|||.||::
Zfish   403 QVSPEDYQQMTNIIQGVMENDYPRLGLDNCDIKEELNKAVQGTGLAFIAFTEAMTHFPASPFWSV 467

  Fly   409 IFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHL 473
            :||:||:.|||.|.||..:.|:|.:.|.|   |..:|....|...|.|.:||....:.|.||..:
Zfish   468 MFFLMLVNLGLGSMFGTIQGILTPIVDTF---KVRKEYLTVGCCVLAFFIGLTFVQRSGNYFVAM 529

  Fly   474 LDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYG 538
            .|.|:|...:|:.|..|.|||:|:|||::|.||::||:||.|.||:...|:||.|:.||.:....
Zfish   530 FDDYSATLPLLIVVLLENIAVAWVYGTDKFFEDLKDMLGFTPYRYYYYMWKFVTPVLLLGLLAAS 594

  Fly   539 LI--GYEPLTYADY----------VYPSWANALGWCIAGSSVVMIPAVAIFKLLS-----TPG-- 584
            :|  |..|.:|:.:          .||.|..|:...:..::::.:|.|.|.:.|:     |.|
Zfish   595 VIQLGLAPPSYSAWNQQLAKEQSLSYPPWGLAVCISLVVTAILPVPVVFILRCLNIIDEKTGGLS 659

  Fly   585 --SLRQRFTILTTPWR---DQQSMAMVLNGVT 611
              |.::...|..|..|   |.:..|.:||..|
Zfish   660 TVSYKKGRIIKDTACRTREDDEDDASLLNAKT 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	226/653 (35%)
slc6a15	NP_001232001.1	SLC5-6-like_sbd	68..646	CDD:294310	220/625 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010