Protein Alignment DAT and slc6a16a

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_021327051.1
• Gene: slc6a16a / 555229
• ZFINID: ZDB-GENE-061009-43
• Length: 693
• Species: Danio rerio
• Alignment Length: 667
• Identity: 216/667 - (32%)
• Similarity: 325/667 - (48%)
• Gaps: 147/667 - (22%)

  Fly    11 KTPTPHDNDNNSI------------------------SDERETWSGKVDFLLSVIGFAVDLANVW 51
            |.|.|.| :|.|:                        .|:|..|..|:.::|:.:||:|.|.|||
Zfish     3 KPPLPSD-ENGSVLTESRSDMALVSADDEGSAGADGQEDDRPAWDSKLQYVLAQVGFSVGLGNVW 66

  Fly    52 RFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLI 116
            ||||||::||||||::.|.::|::.|:|||:||||.||..|:|:|..|..:.|...||||:..::
Zfish    67 RFPYLCHQNGGGAFMLLYVMLLLIIGVPLFFMELAAGQSIRQGSIGVWKHISPRLAGIGYSSCMV 131

  Fly   117 AFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMG 181
            .|:|..||||||||||.:...||...|||..|                    ||
Zfish   132 CFFVALYYNVIIAWSLFYMGNSFQYPLPWEQC--------------------PV----------- 165

  Fly   182 NQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIV 246
              .::.|:|....::            .|..|.::.|..|::  |:.|...|.....|..|||..
Zfish   166 --DMISNQTVKECAA------------SSPTSYFWFRKALDI--SDSIDQSGEFNPIMTGCLLAA 214

  Fly   247 YLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWV 311
            :.|...::.|||.:|.||::|:::||||||:..|||||.|.|:..||:|...|......:.:||.
Zfish   215 WAIVCLAMIKGIKSSAKVMYFSSVFPYAVLICFLIRGLMLDGAIDGIKYMFYPKVEIWGEVQVWR 279

  Fly   312 DAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGY------- 369
            .|||||||:||.|:|.::||:|||..|||.::||::.|.||..||.:|..|:|.|||:
Zfish   280 QAATQVFFALGLGYGSVIAYSSYNPIHNNCHRDAIMVSGINFMTSVLASLVVFVVLGFRAKNIAL 344

  Fly   370 ------------MAHT---------------------------------LGVRIEDV-------- 381
                        ||.|                                 ||..|.|.
Zfish   345 DCVATNVARMAEMAQTGSSQHWRPLFNMSDPKSVVLQDYRQWYSSYGSLLGSNITDCDLEREMSK 409

  Fly   382 ATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNREL 446
            ..||.||.|:.:..|:|..|||.||:.:||:|||.|||.:.||..:.|:|.|.|.|..:.|::.:
Zfish   410 GVEGTGLAFIAFTEAMALFPASPFWSTLFFLMLLNLGLSTMFGTMQGILTPLMDNFRVLGRHKTM 474

  Fly   447 FVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMI 511
            .......|.|::||....:.|.||..:.|.|:|...:::.|.||.::|:||||.:||.:|:..|:
Zfish   475 LTVCSCILGFLIGLLFTQRSGNYFVTMFDDYSATLPLIIVVIFETVSVAWIYGADRFLDDVEVML 539

  Fly   512 GFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANAL---------GWCIAGSS 567
            .:.|...::..|::|..:.::.:....|:   .:.:....|.:|.:..         ||.:...|
Zfish   540 HWRPPVVYRYLWKYVCLLGMVGLLAASLL---RMVFKRPTYTAWNHTTGSEASLEYPGWALVVLS 601

  Fly   568 VVMIPA---VAIFKLLS 581
            :::|.|   |.|..|||
Zfish   602 MLIIVASLPVPIGYLLS 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	209/627 (33%)
slc6a16a	XP_021327051.1	SLC6sbd-B0AT-like	42..617	CDD:271364	206/624 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820