Protein Alignment DAT and LOC4577690

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_061516085.1
• Gene: LOC4577690 / 4577690
• VectorBaseID: AGAMI1_007931
• Length: 602
• Species: Anopheles gambiae
• Alignment Length: 557
• Identity: 184/557 - (33%)
• Similarity: 302/557 - (54%)
• Gaps: 45/557 - (8%)

  Fly    27 RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHN 91
            ||.|:..::|.||.|.::|...|:|:|||....|||||||:||.::|.:.|.||:|:|:|:||..
Mosquito    30 REKWTSNIEFTLSCIAYSVGFGNIWKFPYTALDNGGGAFLIPYLVVLFLIGRPLYYLEMAMGQFC 94

  Fly    92 RKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPN 156
            .:|.:..:. :.|..:|:|....:.......||..|:|.:||:...||::.|||:.|::.|:  .
Mosquito    95 SRGCVKIYD-MAPAMRGVGVGQSVAMVVAMSYYTPILAITLRYLLLSFSSELPWSKCDHSWS--R 156

  Fly   157 CRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYIL 221
            |               ..||.....|.:        ||.:.|...|        :|..||...|
Mosquito   157 C---------------INSDFRGYANVT--------NGLAEDRRNV--------SAELYFTNTI- 189

  Fly   222 ELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTL 286
             ::|:.....||.....:.||||:.:.|....|.||:.::||..:|.|:|||.::.|||...|:|
Mosquito   190 -MHRAPLAEGLGWPDGKLVLCLLVSWSILVVILIKGVRSTGKAAYFLAIFPYVIIFILLAHSLSL 253

  Fly   287 PGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFI 351
            .||..||:::|||.:.:::.|:||::|.||.||||...||.::||:|:|.:.||||:||::.|::
Mosquito   254 EGSLEGIKFFLTPKWESLFSAKVWMEAVTQCFFSLSICFGGIIAYSSFNNFSNNVYRDAMIISWL 318

  Fly   352 NSATSFIAGFVIFSVLGYMAH-TLGVRIEDVATEGPGLVFVVYPAAIATMP-ASTFWALIFFMML 414
            ::.||.:.|.::|.|||.:|| |....|:|:..|||||.|:.||.|||... ....::::||:|.
Mosquito   319 DTFTSIVVGCIVFGVLGNLAHVTHRTSIQDIVREGPGLTFMAYPDAIAKFEYCPQLFSVLFFLMF 383

  Fly   415 LTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAA 479
            ..:|:.|:.|...::|||:.|..|.::..:  .|.|:....|.:.:.....||.....:||.|.|
Mosquito   384 FIVGIGSNLGAITSVITAIRDRCPTVENWK--IVMGVSVSMFCISVVYLAPGGLDLLDVLDTYGA 446

  Fly   480 GYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEP 544
            .|..|....||.:..:||||.:|...||:.|:....|.:|::||..:||:.:..|.:...:.|.|
Mosquito   447 KYVTLTLALFEILTFAWIYGVDRVCRDIKFMLQIETGLFWRICWGIIAPLLVGVILIVSFVDYVP 511

  Fly   545 LTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLS 581
            |.     .|:..|..||.:...:::.:|..|.:.:::
Mosquito   512 LN-----VPAEYNVAGWILYTFAILQLPLWAGYAIMT 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	184/557 (33%)
LOC4577690	XP_061516085.1	None