Protein Alignment DAT and Gat

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 271/600 - (45%)
• Similarity: 391/600 - (65%)
• Gaps: 30/600 - (5%)

  Fly     5 GHIS--KSKTPTPHDNDNN----SISD--ERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNG 61
            ||.:  :|.:||..|..|.    .|..  :|.:||.|:||:|||:|.|:.|.|||||||||||||
  Fly    28 GHTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNG 92

  Fly    62 GGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNV 126
            ||||::||.|.|.:.|||:|:|||||||....|.:..: ::.|:|||||||..:::.:::.||.|
  Fly    93 GGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIV 156

  Fly   127 IIAWSLRFFFASFTNSLPWTSCNNIWNTPNC-RPFESQNASRVPVIGNYSDLYAMGNQSLLYNET 190
            |:||::.:||.|....:||.:|||.|||.|| ..:|.:|.       :..|....|....:.:.:
  Fly   157 ILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNL-------HCWDKIINGTTQKVCSVS 214

  Fly   191 YMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLW 255
            .:|.:||:.:         ....|::.|..|::  |.||.::|.|:|::|..||:|:::|||.:|
  Fly   215 ALNITSLELT---------DPVKEFWERRALQI--SHGIEEIGNIRWELAGTLLLVWILCYFCIW 268

  Fly   256 KGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFS 320
            ||:..:||||:|||||||.:|.|||:||:||||:..||::|:.||||.:..:|||:||.||:|||
  Fly   269 KGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFS 333

  Fly   321 LGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEG 385
            .|.|.|.|:|..||||:.||||||||:...:||:||..||||||||:|:|||.....:.|||..|
  Fly   334 YGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASG 398

  Fly   386 PGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNR-ELFVA 449
            |||.|:|||:|:..:|.|..|:.:||.|||.:||||.|...|..|||:.||:|::.|.| |:|:|
  Fly   399 PGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIA 463

  Fly   450 GLFSLYFVVGLASCTQGGFYFFHLLDRYA-AGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGF 513
            .:.:|.::|||...||||.|.|.:||.|| :|:.:|..:|||.:::||.||.:||.:.|:||||:
  Fly   464 IVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGY 528

  Fly   514 PPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFK 578
            .|..:|:.||....|...|.:..:.::.:.|:.|.||.||.||:|.||..|.||::.||....:.
  Fly   529 YPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWL 593

  Fly   579 LLSTPGSLRQRFTIL 593
            ...|||.|.::...|
  Fly   594 WKRTPGELSEKIRAL 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	262/569 (46%)
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	262/569 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440716
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850