Protein Alignment DAT and blot

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 143/652 - (21%)
• Similarity: 243/652 - (37%)
• Gaps: 219/652 - (33%)

  Fly    16 HDNDNNSIS-------------------------DE--RETWSGKVDFLLSVIGFAVDLANVWRF 53
            ||.|::::|                         ||  ::|.......|:..:...:..|||.||
  Fly   174 HDMDHDAVSKNFSISASAHNITTASNAKLLPAVEDESNKQTKCSVFRGLVLCLCLNLSYANVVRF 238

  Fly    54 P-----YLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGI---- 109
            |     |      |.|:||||.::|.:.|:|:..:|:::||...:||...| |..|:|||.
  Fly   239 PRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTW-RASPIFKGACMIS 296

  Fly   110 GYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNY 174
            .:|..|.|.:|..  ..::|.:....|||  |.||:..|
  Fly   297 RFASWLSAIWVSL--QAVLALAYIGMFAS--NDLPFREC-------------------------- 331

  Fly   175 SDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDM 239
                 .|...|..:...:.|:|               ..|
  Fly   332 -----AGPVKLRLSGYLLTGTS---------------GQE------------------------- 351

  Fly   240 ALCLLIVYLICYF--SLWKGISTSGKV-VWFT-------------ALFPYAVLLILLIRGLTLPG 288
              ||.:.:|..::  .|:.|:..:|.: :|..             ::|.:.::.::|:  .||.|
  Fly   352 --CLQLTFLTPFWRNPLYFGLLAAGLIGLWIVVMLCTHNAKILRRSIFVFGLVGLVLL--CTLTG 412

  Fly   289 SFLGIQYYLTPNFSAIY-------------KAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNN 340
                  :.:..:||..|             ::.:|.:|..||.||:..|||.|....  .|:
  Fly   413 ------WEVRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMIT--GKF--- 466

  Fly   341 VYK-DALLTSFINSATSFIAGFVIFSVL-GYMAHTLGVRIEDVATEG--------PGLVFVVYPA 395
            :|| ||:.||.:         ::.|::| ..:|.||.:...|:::.|        |  :..:|..
  Fly   467 LYKGDAVRTSVV---------YLCFNLLINAIAVTLFMVQFDLSSNGFQNMEELKP--LTAIYDR 520

  Fly   396 A-----------IATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVA 449
            .           :..:..|..:|||....::::        :.|:.|:     .::...|..:|.
  Fly   521 VLNGSREGDSHLLQHLVPSLIYALIILSAMVSI--------TVAVYTS-----TRLVPRRPNYVI 572

  Fly   450 GLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFP 514
            .|..|  ||.:.|.....|....:||....|..::.|:.||.||::||||......|:...||.|
  Fly   573 CLIGL--VVAVISFAAPKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRP 635

  Fly   515 PGRYWQVCWRFVAPIFLLFITVYGLIG---YEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAI 576
            ..|.|...| .:.|..|..|.|:....   |:.|  |:|: |.||..|   ...:.:|:|..|.|
  Fly   636 IFRVWMWLW-VICPAILTGILVWWCADDDQYDLL--AEYL-PRWAPIL---FVLAVIVIIACVQI 693

  Fly   577 FK 578
            |:
  Fly   694 FR 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	137/614 (22%)
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	123/563 (22%)