Protein Alignment DAT and CG4476

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 580
• Identity: 209/580 - (36%)
• Similarity: 314/580 - (54%)
• Gaps: 50/580 - (8%)

  Fly    27 RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHN 91
            |:.|...::||:|.|..:|.|.||||||:...:|||||||:||.::|.|.|.|::|||:.|||.:
  Fly    51 RDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFS 115

  Fly    92 RKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPN 156
            .:|.:..:. ..||.:|:|||.:|....:..||..::|.:||:||.||.:.|||:.|...|. ..
  Fly   116 SRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREEWG-DG 178

  Fly   157 CRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHV-EGFQSAASEYFNRYI 220
            |                   :.|.|.|.|                .|.: ..|.|:...|..|.:
  Fly   179 C-------------------VSASGGQPL----------------QGQLSRNFSSSTQLYLQRIV 208

  Fly   221 LELNRSEGIHD-LGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGL 284
              ||.::.:.: :|.....:||.|.|.:|.....:.:|:.:|||..:..|||||.|:.|||:|.|
  Fly   209 --LNETDSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRAL 271

  Fly   285 TLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTS 349
            ||||::.|:.|:|||.:..:.:.:||.:|.|||||||...|||::.|:|||::.:|||:||.:.:
  Fly   272 TLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVT 336

  Fly   350 FINSATSFIAGFVIFSVLGYMAHTLGVR-IEDVATEGPGLVFVVYPAAIATMPA-STFWALIFFM 412
            .:::.||.::|.:||.:||.:||..|.: |..|...||||.|:.||.|||.... ...::|:||.
  Fly   337 TLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFA 401

  Fly   413 MLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRY 477
            ||..||:.|:.|....|:|.|.|:|..:|  ..:.|..|..:.|:|||...|.||.:...|:|.:
  Fly   402 MLFMLGVGSNVGMVSCIMTVLKDQFVNVK--LWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFH 464

  Fly   478 AAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGY 542
            ...:..||:..||.|||.|||||.|..:|...|:......|:::||..|.|:.:|.|.||.|:..
  Fly   465 GVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTM 529

  Fly   543 EPLTYADYVYPSWANALGWCIAGSSVVMI---PAVAIFKLLSTPGSLRQRFTILTTPWRD 599
            .||:|....:|.....:|||::|..:..:   ...|.||  ...|||:.|......|..|
  Fly   530 RPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFK--QPKGSLKSRINNSIKPHSD 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	207/576 (36%)
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	190/514 (37%)