Protein Alignment DAT and bdg

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 130/666 - (19%)
• Similarity: 235/666 - (35%)
• Gaps: 192/666 - (28%)

  Fly    38 LSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRL 102
            |::||..:.:.|:.||..|.. |.||.||:.:.::.|:.||||.::::.||...|.|.::.| ::
  Fly   505 LALIGCTLGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMW-KI 567

  Fly   103 VPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASR 167
            .|:..|:|.|:|:...::..|..|.:||.|.:....|                   |..:::..|
  Fly   568 SPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVF-------------------PTAARSGYR 613

  Fly   168 VPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTS-AVGHVEGFQSAASEYFNRYILELNRSEGIHD 231
            .              |.:.:...|      |.| |.|::   ....:||||..:|:........|
  Fly   614 W--------------QEMAFPYRY------DASNATGNL---TQTVAEYFNVVVLQRLHLANHPD 655

  Fly   232 LGAIKW-----DMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFL 291
            ...|::     .:|..|.:::...:..|.||:.:.||:.:.....|...|.::..:
  Fly   656 ASGIRFHVNDRQLAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAK--------- 711

  Fly   292 GIQYYLTPN-----FSA------IYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDA 345
             ..|.:.|:     |:|      :..:..|..|..:.|.:.|.....::|..|  :.|.|..|.|
  Fly   712 -FVYVVDPSRIQNIFAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITS--RSHTNANKAA 773

  Fly   346 LLTSFINSATSFIAGFVIFSVL-----------GY------------------------------ 369
            |....|......:.|..:.::|           ||
  Fly   774 LRRDAILLVLFTLIGLGLMALLALCCAQILWQHGYVYVPGSFENPDCYTSIYSLQSNTNPYLLSY 838

  Fly   370 ---------------------MAHTLGVRIEDVATEGPGLVFV--VYPA--AIATMPASTFWALI 409
                                 |.|        |.:....|.|:  ::||  ::|:...|..||.:
  Fly   839 PRSLIPHYSSFIGETYRRNRTMIH--------VESGFQALRFISEIFPAVLSLASDSISWVWAAV 895

  Fly   410 FFMMLLTLGL----------DSSFGG--SEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLAS 462
            .|......||          .|:.|.  |..:::.::.....|....|:   |:..||:|..|.
  Fly   896 AFATFAGFGLAQLCVMWKPISSALGNSTSSVLLSCVTGLLLSIPFATEM---GISILYYVDFLL- 956

  Fly   463 CTQGGFYFFHLLDRYAAGYSILVAVFFEAIAV-SWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFV 526
               ||.:|..:         |..|..|....: ...|..:....|:| :.| ....:..:.|..:
  Fly   957 ---GGSWFIPI---------IWTAQIFGVFLIRGRPYNGDDLVNDLR-LCG-SMSAFLALSWNVL 1007

  Fly   527 APIFLLFITVYGLIGYEPLTYADYVY-------PSWANALGWCIAGSSVVMIPAVAIFK----LL 580
            .||.|:.::|   :.|:......:.|       ..|:..:|..|....:::||..||.:    |.
  Fly  1008 LPIGLITLSV---VDYKASLSNQFYYWRGKSYFTYWSRKMGSLIQIGVLLVIPVTAIIQIYRYLA 1069

  Fly   581 STPGSLRQRFTILTTP 596
            ..|..:.:|..:|..|
  Fly  1070 HGPPDILERIQLLYRP 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	130/666 (20%)
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	107/550 (19%)