Protein Alignment DAT and LOC3291187

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_564070.4
• Gene: LOC3291187 / 3291187
• VectorBaseID: AGAMI1_011017
• Length: 626
• Species: Anopheles gambiae
• Alignment Length: 571
• Identity: 195/571 - (34%)
• Similarity: 316/571 - (55%)
• Gaps: 73/571 - (12%)

  Fly    18 NDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFY 82
            :|..:.:..|:.|...::|:||.|.::|...|:|:|||...|:||||||:||.|:|.:.|.|::|
Mosquito    41 DDTKTTTSTRDKWGRDIEFMLSCIAYSVGFGNIWKFPYTALKHGGGAFLLPYLIVLFIVGRPIYY 105

  Fly    83 MELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTS 147
            :|:.|||.:.:|.:..:. |.|..:|||.|..:..|.|..||..::|.:.|:|.|||:::|||:.
Mosquito   106 LEMILGQFSSRGCVKLYD-LAPAMRGIGVAQTIAMFVVMTYYAPVLAITFRYFVASFSSTLPWSE 169

  Fly   148 CNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVE------ 206
            ||..|  .||                                       :::|.||.:|
Mosquito   170 CNPGW--ANC---------------------------------------VNSSFVGRLEPTNGTA 193

  Fly   207 -GFQSAASEYFNRYILELNRSEGIHD-LGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTA 269
             |.||:|..||.:.:  ::::..:.| ||...|.:|||||..:::....|.:|..::||..:|.|
Mosquito   194 VGLQSSAELYFLKEV--IHKAPSLEDGLGMPDWKLALCLLFAWIVVATILIRGAKSTGKASYFLA 256

  Fly   270 LFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASY 334
            :|||.:::|||::.|.|.|:..||.|::||.:..:...|||.:|.||.||||...:|.::||:|:
Mosquito   257 IFPYVIIIILLLQTLMLDGAMQGILYFITPQWDKLLSIEVWYEAVTQCFFSLSVCYGGIIAYSSF 321

  Fly   335 NKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLG-VRIEDVATEGPGLVFVVYPAAIA 398
            |.:.|||::||::.|::::.||.:||.::|.|:|.:|:..| ..|:.:|.:|.||.|:.||.|||
Mosquito   322 NNFSNNVHRDAVIISWLDTFTSIVAGCIVFGVIGNLAYVSGQPDIQKLARDGAGLTFMTYPDAIA 386

  Fly   399 T---MPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGL 460
            .   :|  ..:|.:||:||..:|:.|:.|.:.:||||:.|:.|:::..:  .|.|..::.:..||
Mosquito   387 KFQFLP--QLFAALFFLMLFIVGVGSNLGVTTSIITAIRDQRPQLRHWQ--VVLGTVTVGYFFGL 447

  Fly   461 ASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRF 525
            ...|.|||.|..::|.|.|.|..|.....|...|:||||.:|...|||.|:|.....||:|||..
Mosquito   448 LYLTPGGFDFLDVIDYYGAKYVTLTFAVLELATVAWIYGVDRICRDIRFMLGIETSFYWRVCWGL 512

  Fly   526 VAPIFLLFITVYGLIGYE----PLTYADYVYPSWANALGWCIAGSSVVMIP 572
            :||...|.|.::....:|    |:.|         |.||..|...:|:.:|
Mosquito   513 IAPAATLLILIFSFADFELQKVPMGY---------NVLGLFIYAIAVLQLP 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	194/562 (35%)
LOC3291187	XP_564070.4	None