DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DAT and CG31904

DIOPT Version :9

Sequence 1:	NP_001261026.1	Gene:	DAT / 36849	FlyBaseID:	FBgn0034136	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_723310.1	Gene:	CG31904 / 319016	FlyBaseID:	FBgn0260479	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	199	Identity:	60/199 - (30%)
Similarity:	93/199 - (46%)	Gaps:	25/199 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PTPHDNDNNSISDERETWSGKVDFLLSVIGFAVD---LANVWRFPYLCYKNGGG-AFLVPYGIML 73
            |..||..       |..|:...||..:....|..   .:.:..|..|   :||. .|::.|.:.:
  Fly    77 PYRHDKC-------RGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGM 131

  Fly    74 VVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFAS 138
            :...:|:|.::..|||.:..|.|:.: |:.|:|||||||::|:......||::.....|.:...|
  Fly   132 LFYSLPIFLIQAFLGQFSSSGTISAF-RVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNS 195

  Fly   139 FTNSLPWTSCNNIWNTPNCRPFESQNAS-RVPVIGNYSDLYAMGNQS----LLYNETYMNGSSLD 198
            ....:||.||||.|||..|...|:.:.. .|.||  ::...|||.||    ||   :.:.|..|.
  Fly   196 IHPVIPWMSCNNSWNTQECSLHENYDVDFAVAVI--FTLALAMGVQSSVIPLL---SQVAGHGLS 255

  Fly   199 TSAV 202
            .:||
  Fly   256 YTAV 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	57/185 (31%)
CG31904	NP_723310.1	SLC5-6-like_sbd	123..>243	CDD:294310	42/122 (34%)
CG31904	NP_723310.1	Cuticle_4	276..344	CDD:292577
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840