Protein Alignment DAT and NAAT1

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 196/585 - (33%)
• Similarity: 308/585 - (52%)
• Gaps: 33/585 - (5%)

  Fly     4 TGHISKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVP 68
            |...|..||      |....:.||..|...::||:|.|..:|.|.||||||:..|:|||||||:|
  Fly    21 TNAASTEKT------DAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIP 79

  Fly    69 YGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLR 133
            |.|:|.:.|.|::|:|:.:||...:|.:..|. :||.|.|:||........:..||:.::|.:|.
  Fly    80 YIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIISYYSSLLALTLY 143

  Fly   134 FFFASFTNSLPWTSCNNIW-NTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSL 197
            :.|.||.:.|||:.|.:.| |..|.||.|            |.|....|..  |.||:..|.|.:
  Fly   144 YLFVSFQSELPWSYCRDEWTNCVNSRPQE------------YVDNLLTGVS--LANESARNLSGI 194

  Fly   198 DTSAVGHVEGFQSAASEYFNRYIL--ELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGIST 260
              .|....|..||::..||...::  :|:.|:|:   |...|.:.|.|.:.:::.:..:.:|:.:
  Fly   195 --VANDETEKLQSSSELYFLNVVIKEKLDISDGV---GDPDWKLTLALFVAWVVIFLVIMRGVKS 254

  Fly   261 SGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGF 325
            |||..:|.|||||.||.:||||.:||.|:..||.::|.|.:..:....||.:|..|.||||..|.
  Fly   255 SGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGS 319

  Fly   326 GVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGV-RIEDVATEGPGLV 389
            |.::.:||||::.:.:|:||::.:.:::.||.:.|..||::||.:||.|.: .|.||...|.||.
  Fly   320 GPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLA 384

  Fly   390 FVVYPAAIATMPA-STFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFS 453
            |:.||.||:...| ...::::||.||..||:.|.......|:|.:.|:|...|..:......:..
  Fly   385 FISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKVALTTSVCG 449

  Fly   454 LYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRY 518
              |::||...|.||.:...|:|.|...|.:.:...||...:.|:||...|.:||..|.......|
  Fly   450 --FLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLY 512

  Fly   519 WQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTP 583
            |:|||.|..|:.::.|.:|.::..||:.|::..:|..||..||.:........|...::.:...|
  Fly   513 WRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHP 577

  Fly   584  583
              Fly   578  577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	190/562 (34%)
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	179/514 (35%)