Protein Alignment DAT and snf-11

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_505873.2
• Gene: snf-11 / 191770
• WormBaseID: WBGene00004910
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 257/594 - (43%)
• Similarity: 381/594 - (64%)
• Gaps: 39/594 - (6%)

  Fly    26 ERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQH 90
            |||.||...||::|.||:|:.|.||||||||||:|||||||:||.|.||..|.|||.:|.:.||.
 Worm     9 EREQWSSWADFIMSCIGYAIGLGNVWRFPYLCYQNGGGAFLIPYCISLVFCGAPLFILETSWGQL 73

  Fly    91 NRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNS-LPWTSCNNIWNT 154
            ...|.:..: ::.|:|||:|.|..::||:::.||.|:::|:..:.:.|||.| :||.:|::.|||
 Worm    74 MSVGGLGMF-KICPIFKGVGIAAAVMAFWLNIYYIVVLSWAATYLYNSFTMSDVPWKNCDHAWNT 137

  Fly   155 PNCR------PFESQNASRVPVIGNYSDLYAMGNQSL-LYNETYMNG--------SSLDTSAVGH 204
            ||||      |.:|..     .|..:.::..:.:..: .|.:.:..|        |:.|.|.|
 Worm   138 PNCRSEYVKIPCDSNR-----TIAEFFNVKVLTHDHIHEYKKQFFVGEKMNWTVCSAADLSVV-- 195

  Fly   205 VEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTA 269
                 |...|::|..:|.:  |.|:.:.|.|:||:||.||:|::|||..::||:..:||||:.||
 Worm   196 -----SPVKEFWNHRVLGI--SSGLENPGGIRWDLALFLLLVWIICYLCIFKGVKWTGKVVYITA 253

  Fly   270 LFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASY 334
            .|||.:|..||||||||.|:.:|:::||.|:||.:.:::|||||.||||||.|.|.|.|:|..||
 Worm   254 SFPYMMLFCLLIRGLTLEGAGVGLEFYLKPDFSKLLESKVWVDAVTQVFFSYGLGLGALVALGSY 318

  Fly   335 NKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIAT 399
            ||::|||||.||...|:||.||..|||||||.:|:||......:.:||..||||:|:.||:.|..
 Worm   319 NKFNNNVYKQALTVCFVNSGTSVFAGFVIFSFIGFMATQQEKSVAEVAQAGPGLLFLAYPSGILQ 383

  Fly   400 MPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKR---NRELFVAGLFSLYFVVGLA 461
            :|.:.||:.:||:|:|.||:||.|...|...||:.||||:|:|   .||:||..:..:.:::||.
 Worm   384 LPYTQFWSCLFFLMVLFLGVDSQFCTMEGFFTAIIDEFPQIRRKKYGREIFVGVICVISYLIGLT 448

  Fly   462 SCTQGGFYFFHLLDRYAA-GYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRF 525
            :.|:||||.|.|.|.||| |:::|..:|||.||:||..|.:|:.|.::.|||:.|..:|:.||.|
 Worm   449 TVTEGGFYVFQLFDFYAASGWALLWLLFFECIAISWSLGIDRWYEHMKSMIGYYPSAWWKFCWVF 513

  Fly   526 VAPIFLLFITVYGLIGYEPL---TYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLR 587
            ..|.....:.::|||.|:||   .| :|.||.|.:..||.::.||::.||..||:....|||:::
 Worm   514 ATPSVCFGVLLFGLIKYQPLRIDAY-NYDYPVWGHIFGWFLSLSSMLCIPGYAIWIWFKTPGTVQ 577

  Fly   588 QRFTILTTP 596
            ::..:|..|
 Worm   578 EKIKLLCRP 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	256/593 (43%)
snf-11	NP_505873.2	SLC6sbd-TauT-like	10..586	CDD:271387	255/591 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820