Protein Alignment DAT and F56F4.3

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_491770.3
• Gene: F56F4.3 / 186398
• WormBaseID: WBGene00018980
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 140/627 - (22%)
• Similarity: 230/627 - (36%)
• Gaps: 128/627 - (20%)

  Fly     1 MSPTGHISKSKTPTPHDNDNNSISDERETWSG-----------KVDFLLSVIGFAVDLANVWRFP 54
            :||||:        |:.|.:...::|.|...|           ::..|||.:..   |.|...|.
 Worm    76 ISPTGN--------PNLNPSKIEAEELEQEIGSRNISRPSTYRQLSLLLSCVTL---LKNNMVFI 129

  Fly    55 YLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHN---RKGAITCWGRLVPLFKGIGYAVVLI 116
            ...:.:||..|.|||.|:|.|.|:|:...||:|.|.:   ..|..|   |:.|:..||.:.::.:
 Worm   130 ECFFNHGGVYFFVPYFIILFVLGVPMAIFELSLAQFSSIPMNGMFT---RMAPMLGGIPWLILCL 191

  Fly   117 AFYVDFYYNVIIAWSLRF-------FFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNY 174
            .    ..|.|.||:..||       |....|.::.|..|::.   ...|.|:...:.::
 Worm   192 R----IIYTVYIAFDPRFLLYAYKSFVTVITGNMNWIHCDDY---KGVRCFDPTWSCKI------ 243

  Fly   175 SDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQS-AASEYF--NRY-ILELNRSEGIHDLGAI 235
                         ||..:||..:....:..:...|. ....||  ..| ::.:..|:...::..:
 Worm   244 -------------NEFRLNGECVKDVHIRKLAQQQDYGLLTYFGLREYRLISIIPSQIYKEINGL 295

  Fly   236 K-WDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPY-----AVLLILLIRGLTLPGSFLGIQ 294
            . .|..|..|:..||..|..:||......:..|....|.     ||:|:....|......|  .|
 Worm   296 DIMDNILAALVFLLIAGFITYKGHRFFASLAGFFVFLPILGMIPAVILVYYDVGSRKKHFF--NQ 358

  Fly   295 YYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIA 359
            .....:.:.|::...|::||.....::....|.|:|..|...:.:|..|||:|.:...:....:.
 Worm   359 ILKNNDITKIFELSAWLNAARVTVKTVYIADGTLMALGSRADFRHNFIKDAVLLAASGATYRLLL 423

  Fly   360 GFVIFSVLGYMAH--------TLGVRIEDVATEGPGLVFVVYP--AAIATMPASTFWALIFFMML 414
            .|.|..:| |:|:        |:..|.:.|......|.|...|  |.....|..||:  ::.|:.
 Worm   424 CFGILPIL-YVANDILYPFAKTVYARGDLVQFHAIELFFSALPSYAIPGISPTVTFF--VYAMLY 485

  Fly   415 LTLGLDSSFGG-----SEAIITALSDEFPKI-----KRNRELFVAGLFSLYFVVGLASCTQG--- 466
            .|:..  :|..     .|.:|.||...||::     |..|...:....:|...:.:.|....
 Worm   486 GTINF--AFVAYQVITFEMLINALHHLFPRLLYLKQKSVRICIIMATVTLLLFLYILSLPYKQLA 548

  Fly   467 -GFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRY---------WQV 521
             |:.....:|.|..|. :...||.:.|:||.:||..|...:...|:...|..|         ..|
 Worm   549 VGYQKELAIDDYVVGL-VSTTVFIQLISVSIVYGYKRLLINFLTMLKHHPVTYKLVEKCRVFLYV 612

  Fly   522 CWRFVAPIFLLF----------------ITVYGLIGYEPLTY 547
            .|.|..||..|.                :.:|..|...||.|
 Worm   613 MWAFFLPISCLVSICSIIVKKYQIYHWPLVLYAAISALPLIY 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	133/601 (22%)
F56F4.3	NP_491770.3	SLC5-6-like_sbd	73..620	CDD:382020	132/591 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810