Protein Alignment DAT and snf-9

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_503077.2
• Gene: snf-9 / 178512
• WormBaseID: WBGene00004908
• Length: 713
• Species: Caenorhabditis elegans
• Alignment Length: 685
• Identity: 201/685 - (29%)
• Similarity: 316/685 - (46%)
• Gaps: 111/685 - (16%)

  Fly     2 SPTGHISKSKTPTPHD--------NDNNSISDERET--------WSGKVDFLLSVIGFAVDLANV 50
            |||...|.|.:....|        .|:.|..:..|:        |..:::||||.:|.||.|.|:
 Worm    10 SPTQRRSPSDSSAAEDQRIATTIVRDSGSSKEIEESQADPCRGAWGNQIEFLLSTLGMAVGLGNI 74

  Fly    51 WRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVL 115
            ||||...|.|||.||||||....::.|:|..|:|..|||::|..|...:.|..|:.:|:|:..|.
 Worm    75 WRFPTRAYNNGGSAFLVPYVACALLFGLPAVYLEFLLGQYHRTTAPIIFRRFAPILQGVGWMAVA 139

  Fly   116 IAFYVDFYYNVIIAWSLRFFFASFT--NSLPWTSCNNIWNT----------PNCRPFESQNASRV 168
            ::..|..||.:||.|| ..:.||..  ::..|..|.|.||.          |.|..|.:......
 Worm   140 VSSLVAIYYIIIIGWS-TVYMASIVMGHTSKWNRCGNSWNNAESCVDSGLQPLCASFNATGNETS 203

  Fly   169 PVIGNYSD-----LYAMGNQS------LLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILE 222
            ||..|.|.     .|...|.|      |.:|:|.|                .:|..:||..|:::
 Worm   204 PVWANLSSEGRGKFYIYLNTSCYDKVDLEFNKTKM----------------IAATEQYFFDYVVK 252

  Fly   223 LNRSEGIHDLGAIK----WDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRG 283
              .::|..:..:|.    :.|..|.|||.||    ||||:...||..:.....||.::::|..||
 Worm   253 --PTDGFLEFSSINFKSFFGMNACWLIVVLI----LWKGVGYMGKASYVIVTLPYFIIILLFFRG 311

  Fly   284 LTLPGSFLGIQYYL-TPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALL 347
            :||.|:..||.||| .|::|.::....|.:|..|:.||||.|:|.|:..||::|.:||.::|||:
 Worm   312 ITLDGAEDGIYYYLGNPDWSKVFMPATWGEALKQLCFSLGIGYGGLIGMASFSKPNNNCFRDALI 376

  Fly   348 TSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFM 412
            ....::..|.:.|..:||.||::|...|..:.:|..:|..|.||.:|.|:..||....|:.:||:
 Worm   377 VIIGDTMMSLVGGAAVFSTLGFLAKKKGCSVAEVVNDGFSLAFVAFPEALGRMPLPELWSFLFFL 441

  Fly   413 MLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSL-YFVVGLASCTQGGFYFFHLLDR 476
            ||..||:.:.........:::.|:|..: |.|:..||.|:.| .:|:|:...|.||||:|.:.|.
 Worm   442 MLFFLGISTEVAYVNVFCSSICDQFVNL-RKRKWLVAVLWCLVLYVLGVVMVTDGGFYWFIMFDE 505

  Fly   477 YAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGR----------YWQVCWRFVAPIFL 531
            ||||.|...||..|.:.|:::||......|:::|.|....:          |:...|.||.|:..
 Worm   506 YAAGVSSCCAVTAEVLIVAYVYGRRNQLADMKEMFGESKNKCTSWIGQHSPYFGFNWMFVTPVLG 570

  Fly   532 LFITVYGLIGYEPLTYAD---YVYPSWANALGWCIAGSSVVMIPAVA------------------ 575
            ..:.|...|...|....:   .:||...:.:||.:....:.::|..|
 Worm   571 SILIVLASIRQYPYQTDENKPNMYPLAFDIVGWAVCLLPMALVPIFAFCAFVEFKRKGHDLRALF 635

  Fly   576 -----------IFKLLSTPGSLRQRFTILTTPWRD 599
                       |::.:::....:|:......||.|
 Worm   636 MKQRQLKSFGRIYQTMASKDRAKQKILPDREPWDD 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	190/648 (29%)
snf-9	NP_503077.2	SLC6sbd	52..577	CDD:271359	179/548 (33%)