Protein Alignment DAT and snf-7

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_499702.2
• Gene: snf-7 / 176723
• WormBaseID: WBGene00004906
• Length: 705
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 199/642 - (30%)
• Similarity: 318/642 - (49%)
• Gaps: 69/642 - (10%)

  Fly     2 SPT-GHISKSKTPTPHDNDNNSISD-------ERETWSGKVDFLLSVIGFAVDLANVWRFPYLCY 58
            :|| |.:...|.||..||...:..:       :|:.:.| ::..||.:|.||.|.|:||||...|
 Worm    33 APTKGPVQPQKKPTTVDNGRRAYRNQVVVENVDRQAFRG-IESFLSSLGQAVGLGNIWRFPTTAY 96

  Fly    59 KNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFY 123
            ||||.:||:.|.:..::..:|..:||.||||:..|.....:.|::|:.:|:|:...|:...:..|
 Worm    97 KNGGLSFLIAYVVCGILFAVPAIHMEFALGQYAAKSPPAAFRRMMPILEGVGWMTCLVGAIIGVY 161

  Fly   124 YNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYA--MGNQSLL 186
            |.::|:|.:.:.| :...:...:.|||.||         :|.|.:...|....|.:  |.|.||:
 Worm   162 YMIVISWIVLYLF-NIIYATKISKCNNDWN---------KNRSTICYEGVKQKLCSGYMLNSSLV 216

  Fly   187 YNETYMNGSSLDTSAVGHVEG-FQSAAS--------EYFNRYILELNRSEGIHDLGAIKWDMALC 242
            ......|.|.  .|.:.:::| .|:|.:        ::|..::::  .|.|..|..:|...|...
 Worm   217 MTNLTRNASV--HSKMMYIDGKCQNATNMKLAVGTEQFFTNFVVK--PSTGFTDFNSINVPMLAA 277

  Fly   243 LLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYL--TPN----- 300
            :.:.::|...||.:|:...||:.::|.|.|||:::.|:||||||.|:..|:.:..  .||
 Worm   278 VAVCWVIAIISLIRGMKAIGKLSYYTVLLPYAIIIALMIRGLTLEGASTGLHFLFWGKPNEYGHY 342

  Fly   301 -FSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIF 364
             |:.:|..:||:.|..|:.|||..|.|.|:...||||...|.|:||.|....::..|.:.|..:|
 Worm   343 DFAGLYDPDVWIAALMQMCFSLSIGQGGLMNIGSYNKKTYNWYRDAYLVVLCDTLMSLLGGTAVF 407

  Fly   365 SVLGYMAHTLGVRI------EDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSF 423
            |.||::|....:.|      .:|..||..|.|:||..|||.||....|..:||:||..||:.:..
 Worm   408 STLGFLAEQRNISISNPKGFNEVVQEGHALAFIVYTEAIAQMPYPFLWYALFFVMLFLLGISTEI 472

  Fly   424 GGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVF 488
            ...|.:.:.|:|.|..::::|.:.|..:.:.:|::||...:..|||:|.|.|.|:||.|..:...
 Worm   473 VIIETVCSCLADRFHYLRQHRWITVVTVSTTFFLLGLVMTSDAGFYWFDLYDEYSAGVSATIGTA 537

  Fly   489 FEAIAVSWIYGTNRFSEDIRDMIGFP---------PGRY-WQVCWRFVAPIFLLFITVYGLIGYE 543
            ...:.|.|.||.:.|..|||:|...|         ||.| |.:.||||.||..|.| ::..|..:
 Worm   538 IMCLTVCWCYGLDNFRADIREMWEEPESRLDKYLGPGAYVWTIVWRFVTPICCLVI-MFAWIWDK 601

  Fly   544 --PLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWR 598
              |.......||...:|.||.:|.....::|..|.|.:        :||..|..|.|
 Worm   602 KYPFKGDSKKYPPVFDAFGWFVAALPFFVVPVFAGFAI--------KRFKDLNIPIR 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	189/606 (31%)
snf-7	NP_499702.2	SLC6sbd	70..598	CDD:271359	174/543 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820