Protein Alignment DAT and snf-5

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_496735.1
• Gene: snf-5 / 174923
• WormBaseID: WBGene00004904
• Length: 728
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 174/595 - (29%)
• Similarity: 297/595 - (49%)
• Gaps: 54/595 - (9%)

  Fly    14 TPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGI 78
            ||.:.:    .::|:.:....:|:|:.:|.||.|.|:||||...|.|||.|||:||.....:.|:
 Worm    73 TPPEEE----EEKRDGFGNSFEFVLTSLGLAVGLGNIWRFPTRAYNNGGSAFLIPYLTCAFLFGL 133

  Fly    79 PLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAW-------SLRFFF 136
            |..|.|...||:..|.....:.|:.|:.:|:|:..|.:|..|..||.||::|       ..|..|
 Worm   134 PAVYFEFLTGQYQGKSPPVIFRRVRPILEGVGWMGVFVAALVAIYYIVIVSWISIYMINICRGHF 198

  Fly   137 ASFTNSLPWTSCNNIWNT-PNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNET--------YM 192
            |.      |:.|||.||. .:|.....|...:     |::.:.|   .|.|:|.:        |.
 Worm   199 AL------WSHCNNDWNNGTSCITMADQYLCK-----NHTKVMA---NSTLWNSSLPIPDKMVYF 249

  Fly   193 NGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKG 257
            ||:..|.:..    ...:|..:||..||::  .|.|:.|.|...|.:...:.:.:|:....:.||
 Worm   250 NGACQDANGT----DVSTATEQYFMTYIVQ--PSSGMLDFGGFNWPVFAAMSVCWLLTGLGILKG 308

  Fly   258 ISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQ-YYLTPNFSAIYKAEVWVDAATQVFFSL 321
            ....||:.:.:.|.||.::::|.|.|:...||.:|:: |:.|||::.:|:.:.|.:|..|:.|||
 Worm   309 AKIMGKISYVSVLVPYVLVVVLFINGVFQDGSGVGLEMYFGTPNYTKLYEQDTWTEALKQLCFSL 373

  Fly   322 GPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGP 386
            ..|.|.|::.:||:...||:::|||:....::..|.:.|..:|:.|||:|...|..::||...|.
 Worm   374 SVGHGGLISLSSYSPKRNNIFRDALIVIIGDTTMSLVGGGAVFATLGYLAKATGQDVKDVVKSGL 438

  Fly   387 GLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGL 451
            .|.|||||.|:..||....|..|||:||..||..:.....:...:.:.|::|:.:..:.:.|...
 Worm   439 SLAFVVYPEAMTRMPVPWLWCFIFFLMLFLLGASTEIALVDVFCSCIYDQYPRFRNRKWIVVIAW 503

  Fly   452 FSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPG 516
            .|:.:.:||...|:.|:|:|.:.|.||||:|.:..|..|.:.:.:|||.....:||.:::|....
 Worm   504 CSVLYCIGLVFSTRAGYYWFEMFDEYAAGFSSVCTVVCELLVMMYIYGFRNVRDDITEVVGHARN 568

  Fly   517 R----------YWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMI 571
            :          |:...|..::|...|.:.....:...|......:||:..:..||.::...|:::
 Worm   569 KFTGAIGAHSWYFTANWMVISPSIALILVGLSFVREYPYMGRHDIYPAVFDIFGWFLSFLPVIIV 633

  Fly   572 PAVAIFKLLS 581
            |   ||.||:
 Worm   634 P---IFMLLN 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	172/582 (30%)
snf-5	NP_496735.1	SLC6sbd	83..601	CDD:271359	160/537 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810