Protein Alignment DAT and snf-2

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_492396.2
• Gene: snf-2 / 172701
• WormBaseID: WBGene00004901
• Length: 746
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 194/600 - (32%)
• Similarity: 306/600 - (51%)
• Gaps: 68/600 - (11%)

  Fly    26 ERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQH 90
            :|:.:.| ::.|||.:|.|:.|.|:||||.:.|:|||.:||:.|.|...|..:|..:||.||||:
 Worm   108 DRQAFRG-IESLLSSLGQAIGLGNIWRFPTVAYQNGGTSFLIVYIICAFVFAVPAIHMEFALGQY 171

  Fly    91 NRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASF-TNSLPWTSCNNIWNT 154
            ..|.....:.|::|..:|:|:...::...:..||.::|:|.:.:....| .|::  ..|:|.||.
 Worm   172 AAKSPPAVFRRIMPALEGVGWMTCIVGAVIGVYYMILISWIVLYIINIFYVNNM--GRCDNPWNQ 234

  Fly   155 PNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNET-------------YMNGSSLDTSAVGHVE 206
            .||  ::....||... |.||::.|  |.|...|.|             |:||...|.:.:
 Worm   235 NNC--YDGSEQSRCNK-GLYSNMTA--NASSFLNTTMAPLMSSGSKRILYINGKCQDATNM---- 290

  Fly   207 GFQSAASEYFNRYILELNRSEGIHD--------LGAIKWDMALCLLIVYLICYFSLWKGISTSGK 263
            ..:....::|::.:  :..|.|..|        |||:    |||.:|..::    |.:|:...||
 Worm   291 SVEVGTEQFFSKSV--IRPSAGFTDFNSINLPILGAV----ALCWVIAAVV----LIRGMKAIGK 345

  Fly   264 VVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYL--TPNFSAIYKAEVWVDAATQVFFSLGPGFG 326
            :.:.|.:.||.:::.|||.|::|||:..|: |:|  ..:|:.:||.|.|..|..|:.|||..|.|
 Worm   346 LSYVTVILPYFIIVSLLICGVSLPGAKDGL-YHLFGQTDFNYLYKRETWTAALQQICFSLSIGQG 409

  Fly   327 VLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIED------VATEG 385
            .|:..|||||...|.|:|..:..|:::..|.:.|..:||.||::|:..|:...|      :..||
 Worm   410 GLMNIASYNKKTYNWYRDVYIIVFLDTLMSILGGITVFSTLGFLAYERGINSTDIDAFNHIVKEG 474

  Fly   386 PGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAG 450
            ..|.|:||..|||.||....|..:||:||..||:.:.....|.:.:.|:|.|..::..|.|.|..
 Worm   475 HALAFIVYTEAIAEMPVPYLWYALFFIMLFLLGISTEVVIVEIVCSCLADRFRYLRERRWLTVLS 539

  Fly   451 LFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFP- 514
            :.:::|::||...|..|||:|.:.|.|:.|.|.........:.|.|.||||.|.|||..|.|.|
 Worm   540 VSAVFFLLGLVMTTDAGFYWFDMFDEYSTGISATFGTAIMCMTVFWCYGTNHFREDIAVMWGEPE 604

  Fly   515 --------PGRY-WQVCWRFVAPIFLLFITVYGLIGYE---PLTYADYVYPSWANALGWCIAGSS 567
                    |..| |.:.|:||.|:..|.  :.||..:|   |......:||...:||||.||...
 Worm   605 SWLATCLGPAAYFWTLIWKFVTPVCSLL--MMGLWIWEKKYPHKGDGKIYPPVFDALGWFIAVVP 667

  Fly   568 VVMIPAVAIFKLLST 582
            .::||..||..:::|
 Worm   668 FLVIPGFAIAAVINT 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	193/598 (32%)
snf-2	NP_492396.2	rplD	5..>122	CDD:184900	5/14 (36%)
		SLC6sbd	113..638	CDD:271359	178/549 (32%)