Protein Alignment DAT and snf-1

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_491491.2
• Gene: snf-1 / 172119
• WormBaseID: WBGene00004900
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 132/587 - (22%)
• Similarity: 247/587 - (42%)
• Gaps: 91/587 - (15%)

  Fly    23 ISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELAL 87
            :.:.|:.|..|::|::|.:.:...:.|....|.|..:|||.||...|.|::.|..:|...||:::
 Worm    17 VEEWRDLWPSKIEFIVSAMAYLFAMTNFLNLPKLILENGGVAFAAAYAIVVGVLCMPTMVMEMSI 81

  Fly    88 GQHNRKGAITCWGRLVPLFKGIG-----YAVVLIAFYVDFYYNVIIAWSLRFFFASF---TNSLP 144
            ||...:..:..:..|.|:|:|||     :.:|::|....|...:.:  .|.::|.:|   .:.||
 Worm    82 GQVTGRAPVLAFYHLFPVFRGIGVSQILFTMVVLACMTKFLSTLCL--FLYYYFWTFHAGRSGLP 144

  Fly   145 WTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQ 209
            |.         ||:.|....:......|:.:::..:.|:        :|....::|.:
 Worm   145 WL---------NCKAFPEFVSQPCREAGSITNITQINNR--------LNTIQAESSMM------- 185

  Fly   210 SAASEYFNRYILELNR-SEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPY 273
                    :::..|.| ||.|.|....::.:.:....:::..:.::..|:...||.|.|..:..:
 Worm   186 --------QFLTTLERPSESIADFKDFQYPILIAQGAIWIAIFVAICFGVRFVGKTVAFVLMLAF 242

  Fly   274 AVLLILLIRGLTLPG--SFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNK 336
            :.||:..:|..||.|  ..|.| |:...::..:...:||..|..|.....|.|:|..:..:||.|
 Worm   243 SSLLVFFLRSATLGGVTEILEI-YWKATDWEKLADYQVWRLAIEQAILGTGIGYGAFITMSSYMK 306

  Fly   337 YHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPG-----LVFVVY--- 393
            ..||:..|::..|..:...||:....|..::||::..||:...::...|..     |.:|.|
 Worm   307 RSNNLVCDSIFLSVWHLIISFVQTMSIICIVGYLSMKLGIHPTELLETGEDQMWYMLAYVSYLPK 371

  Fly   394 --PAAIATMPASTFWALIFFMMLLTLG-LDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLY 455
              ...:.|:...|.:::|..:.|..|. .:.:||          :.:.|..|.   |...||...
 Worm   372 LWSGVLLTICICTMFSVITILALSVLSTFEDAFG----------ENWSKCCRR---FFLALFVCL 423

  Fly   456 FVVGLA--SCTQGGFYFFHLLDR---YAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPP 515
            |..||.  ..|..|.:.:.|..|   |...|.||.|   |..|.:|.|..::..:|:.:|:.
 Worm   424 FCFGLTVYFATNAGRHAYELATRSIKYCTIYFILTA---ELFATAWFYCAHKLGKDLHNMMR--- 482

  Fly   516 GRYWQVCWRFVAPIFLLFITVYGLI--GYEPLTYADYVYPSWANAL-GWCIA---GSSVVMIPAV 574
                ..|.......||.|..:..::  |...|...||.:.|::..: .|..:   |.::.|:|.:
 Worm   483 ----SRCCSCFGHFFLYFTYLLPILPAGVAFLNALDYKFSSFSAPIHEWKYSEYVGIAIAMVPLI 543

  Fly   575 AI 576
            .|
 Worm   544 PI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	132/583 (23%)
snf-1	NP_491491.2	SNF	21..554	CDD:264495	132/583 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810