Protein Alignment DAT and slc6a7

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_002940131.3
• Gene: slc6a7 / 100487063
• XenbaseID: XB-GENE-479449
• Length: 634
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 268/603 - (44%)
• Similarity: 376/603 - (62%)
• Gaps: 41/603 - (6%)

  Fly     6 HISKSKTP----TPHDNDNNSIS----DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGG 62
            |:.:..||    :|.|.|:..:.    ::|..||||:|||||.||:.|.|.|||||||..|.|||
 Frog     8 HLKQPVTPDLLMSPSDRDDTELDIEYPEDRGNWSGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGG 72

  Fly    63 GAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVI 127
            ||||:||.|||.:.|||||:|||:|||.:..|.:..| ::.|||||:|..::||...|..|||:|
 Frog    73 GAFLIPYFIMLAICGIPLFFMELSLGQFSSLGPLAVW-KISPLFKGVGMGMLLIVALVAIYYNMI 136

  Fly   128 IAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYM 192
            ||:.|.:.|||.|:||||..|.|.|||..|.......||               |.:||.|
 Frog   137 IAYVLFYLFASLTSSLPWEHCGNWWNTDLCLDHHVIRAS---------------NSALLVN---- 182

  Fly   193 NGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKG 257
                        :....|.:.||::||:|.:..|.||.|.|.::|.:.||||:.:.|.|..:.||
 Frog   183 ------------ISNTVSPSEEYWSRYVLHIQGSSGIGDPGQLRWKLCLCLLLSWTIVYLCILKG 235

  Fly   258 ISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLG 322
            :.:|||||:|||.|||.:|::|||||:||.|:::||::||||.|..:..::||::||.|:|:|||
 Frog   236 VKSSGKVVYFTATFPYIILVMLLIRGVTLEGAWIGIKFYLTPQFEHLLTSKVWIEAALQIFYSLG 300

  Fly   323 PGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPG 387
            .|||.||.:||||.:|.|:|:|..:.:..|:.||.:|||.||||||||:..|||.::.||..|||
 Frog   301 VGFGGLLTFASYNTFHQNIYRDTFIVTLGNAFTSILAGFAIFSVLGYMSQELGVPVDQVAKAGPG 365

  Fly   388 LVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFP-KIKRNRELFVAGL 451
            |.|||||.|:..:|.|.||:.:||.|||||||||.|...|.|:||::|||| .::..:.:|.|.:
 Frog   366 LAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFMETIVTAITDEFPYYLRPKKAVFSAII 430

  Fly   452 FSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPG 516
            ....|::||...|.||.|:..|||.|:||:.:||.|....::||.:||...|..||:.|:||.||
 Frog   431 CVALFLLGLILATDGGMYWLVLLDDYSAGFGLLVIVITFCLSVSRVYGIKNFCRDIQMMLGFKPG 495

  Fly   517 RYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLS 581
            .|::.||.|::|:.|:.:..|.::.|:|..|..|.:|.|:.|||..:...|.:|||...:..:|.
 Frog   496 LYFKACWIFLSPVTLMCLLAYSILKYQPSQYGSYKFPLWSEALGILMGLLSCMMIPIGMLVAILK 560

  Fly   582 TPGSLRQRFTILTTPWRD 599
            ..|||.:|....:.|..|
 Frog   561 EEGSLWERIRQASRPAMD 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	260/570 (46%)
slc6a7	XP_002940131.3	SLC5-6-like_sbd	37..581	CDD:382020	262/574 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010