Protein Alignment DAT and slc6a15

DIOPT Version :9

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 219/635 - (34%)
• Similarity: 335/635 - (52%)
• Gaps: 126/635 - (19%)

  Fly    19 DNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYM 83
            :.:.|.|||..|:.|:.::|:.:||:|.|.|||||||||.||||||:||||.|:|::.|||:|::
 Frog    53 EGSDIDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPVFFL 117

  Fly    84 ELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSC 148
            ||::||..|:|:|..|..:.|...|||:|..::..:|..||||||.|||.:|..||.:.|||..|
 Frog   118 ELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQSFQHPLPWDQC 182

  Fly   149 NNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAAS 213
                                |::.|.|:.:.                        ..|..:|:|:
 Frog   183 --------------------PLVKNASNTFV------------------------EPECEKSSAT 203

  Fly   214 EYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLI 278
            .|: .|...||.|..|.:.|.:.|.|.||||..:::...::.|||.:||||::|::||||.||..
 Frog   204 TYY-WYREALNISNSITEGGGLNWKMTLCLLAAWILVCLAMIKGIQSSGKVMYFSSLFPYVVLTC 267

  Fly   279 LLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYK 343
            .|:|.|.|.||..||::..||....:.:.:||.:|||||||:||.|||.::|::||||..||.:.
 Frog   268 FLVRALLLNGSVDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHF 332

  Fly   344 DALLTSFINSATSFIAGFVIFSVLGYMAH------------------------------------ 372
            ||:|.||||..||.:|..|:|:|||:.|:
 Frog   333 DAVLVSFINFFTSVLATLVVFAVLGFKANIMNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSS 397

  Fly   373 ----------------------TLGV---RIED---VATEGPGLVFVVYPAAIATMPASTFWALI 409
                                  :||:   :|||   .:.:|.||.|:.:..|:...|||.||:::
 Frog   398 MSAQDYNLVYYIFQKIKEEEFDSLGLDSCQIEDELNKSVQGTGLAFIAFTEAMTHFPASPFWSVM 462

  Fly   410 FFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLL 474
            ||:||:.|||.|.||..|.|||.:.|.|   |..:|....|...|.|.:||....:.|.||..:.
 Frog   463 FFLMLVNLGLGSMFGTIEGIITPIVDTF---KVRKEPLTVGCCLLAFCIGLLFVQRSGNYFVTMF 524

  Fly   475 DRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGL 539
            |.|:|...:|:.|..|.:|::|:||.::|.:|::||:||.|.:|:...|::::|:.|..:.:..:
 Frog   525 DDYSATLPLLIVVILENVAIAWVYGIDKFMDDLKDMLGFTPYKYYYYMWKYISPVLLTILLMASI 589

  Fly   540 I--GYEPLTYADYV----------YPSWANALGWCIAGSSVVMIPAVAIF 577
            :  |:.|..|..::          ||.|..|:  ||:.....::|...:|
 Frog   590 VQMGFSPPGYYAWIAEKASEERISYPPWGLAV--CISLIVFALLPVPVVF 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	216/627 (34%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:382020	216/627 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920